Results 141 to 150 of about 538,878 (317)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Comparison of the Effect of Insole with Different Widgets on Static and Dynamic Balance

open access: yesپزشکی بالینی ابن سینا, 2020
Background and Objective: Improving control of balance is essential for carrying out daily activities of life as a basic functional ability. The importance role of external intervention on the foot balance as main point of contact between land and body ...
Ali Yalfani   +2 more
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

External constraint and financial crises with balance sheet effects [PDF]

open access: yes
This paper investigates the dynamic implications of Krugman’s (1999) model of financial crises with balance-sheet effects, which has a considerable impact on the literature as well as the teaching of international financial crisis.
Dai, Meixing
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

An econometric model of the balance of payments of Venezuela

open access: yes, 1989
PhDThe fundamental purpose of this study is to build an econometric model of the Venezuelan Economy to concentrate primarely on the following: first, to analyse the effects of monetary, fiscal and external disturbances on expenditures, prices and on ...
Escalante, Alexander Jose Guerrero
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

A Dynamic Factor Analysis of Financial Contagion in Asia [PDF]

open access: yes
In this paper we compared the performance of country specific and regional indicators of reserve adequacy in predicting, out of sample, the balance of payment crisis affecting the South East Asian region during the 1997-98 period. A Dynamic Factor method
Andrea Cipollini, George Kapetanios
core  

The Effect of PETTLEP Imagery and Balance Practice on Dynamic Balance of the Elderly

open access: yes, 2016
In recent years, researchers have become interested in examining the effect of PETTLEP imagery on motor performance and how PETTLEP imagery can improve the performance.
Hasan Khalaji   +2 more
core   +1 more source

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