Results 121 to 130 of about 4,934,646 (307)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Dynamic Calibration of the NASA Ames Rotor Test Apparatus Steady/Dynamic Rotor Balance [PDF]

open access: yes, 1996
The NASA Ames Rotor Test Apparatus was modified to include a Steady/Dynamic Rotor Balance. The dynamic calibration procedures and configurations are discussed.
Peterson, Randall L.   +1 more
core  

An Interpretable Machine Learning Framework for Athlete Motor Profiling Using Multi-Domain Field Assessments: A Proof-of-Concept Study

open access: yesApplied Sciences
Early detection of modifiable motor deficits is essential for safe, long-term athletic development, yet most field screens provide only binary risk scores.
Bartosz Wilczyński   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Effect of 8-Week Strength Training, Balance Training and Combined Training on the Dynamic and Static Balance of the Elderly Inactive Men

open access: yesPhysical Treatments, 2019
Purpose: of the most critical changes in the elderly is the weakness in keeping their balance that can expose them to severe injury risks. The purpose of this study was to evaluate the effects of 8 weeks of strength, balance, and combined (strength and ...
Majid Barzegari   +2 more
doaj  

Motion Planning and Control with Environmental Uncertainties for Humanoid Robot

open access: yesSensors
Humanoid robots are typically designed for static environments, but real-world applications demand robust performance under dynamic, uncertain conditions.
Zhiyong Jiang   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Balance-of-payments constrained economic growth in Brazil [PDF]

open access: yes
This paper applies Thirlwall’s basic balance-of-payments constraint model to Brazilian economic growth in the period 1955-98, using cointegration technique.
Frederico Gonzaga Jayme Junior
core  

On the Analytics of the Dynamic Laffer Curve [PDF]

open access: yes
In this paper, we analyze government budget balance within a simple model of endogenous growth. For the AK model, simple analytical conditions for a tax cut to be self-financing can be derived.
Agell, Jonas, Persson, Mats
core   +2 more sources

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