Results 141 to 150 of about 7,624,306 (408)
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Balancing indivisible real-valued loads in arbitrary networks [PDF]
arXiv, 2013 In parallel computing, a problem is divided into a set of smaller tasks that are distributed across multiple processing elements. Balancing the load of the processing elements is key to achieving good performance and scalability. If the computational costs of the individual tasks vary over time in an unpredictable way, dynamic load balancing aims at ...
arxiv
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
The impact of association agreements on trade flows and the trade balance: Evidence from the CEEC-4 [PDF]
, 2009 In this paper we focus on the trade balance effects of free trade agreements between the EU-15 and the CEEC-4 countries using a dynamic panel data approach.
Caporale, GM, Rault, C, Sova, A, Sova, R
core
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Comparison of the Effect of Insole with Different Widgets on Static and Dynamic Balance
پزشکی بالینی ابن سینا, 2020 Background and Objective: Improving control of balance is essential for carrying out daily activities of life as a basic functional ability. The importance role of external intervention on the foot balance as main point of contact between land and body ...
Ali Yalfani +2 more
doaj
Effects of training on postural control and agility when wearing socks of different compression levels [PDF]
, 2017 Study aim: The aim of this study was to evaluate the effects of training while wearing socks differing in compression level (clinical, sub-clinical, regular) on performance of static and dynamic balancing and agility tasks in healthy, physically active ...
Akseki +37 more
core +3 more sources
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Physical Treatments, 2019 Purpose: of the most critical changes in the elderly is the weakness in keeping their balance that can expose them to severe injury risks. The purpose of this study was to evaluate the effects of 8 weeks of strength, balance, and combined (strength and ...
Majid Barzegari +2 more
doaj
, 2017 Background and Purpose: The purpose was to investigate the effects of fatigue on balance in individuals with Parkinson’s disease (PD). Because falls in this population can have deleterious consequences, it is important to understand the influence of ...
Baer, Michael +2 more
core