Results 141 to 150 of about 1,275,522 (345)

Analysis of high velocity impact on hybrid composite fan blades [PDF]

open access: yes
Recent developments in the analysis of high velocity impact of composite blades are described, using a computerized capability which consists of coupling a composites mechanics code with the direct-time integration features of NASTRAN. The application of
Chamis, C. C., Sinclair, J. H.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Multidisciplinary analysis of actively controlled large flexible spacecraft [PDF]

open access: yes
The control of Flexible Structures (COFS) program has supported the development of an analysis capability at the Langley Research Center called the Integrated Multidisciplinary Analysis Tool (IMAT) which provides an efficient data storage and transfer ...
Cooper, Paul A.   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Assessment of a human computer interface prototyping environment [PDF]

open access: yes
A Human Computer Interface (HCI) prototyping environment with embedded evaluation capability has been successfully assessed which will be valuable in developing and refining HCI standards and evaluating program/project interface development, especially ...
Moore, Loretta A.
core   +1 more source

Structural optimisation problem in support to building retrofitting decision [PDF]

open access: yes, 2005
Various analysis methods, either linear elastic or non-linear, static or dynamic, are available for the performance analysis of existing buildings. Despite its advantages, it must be admitted that non-linear time history analysis can frequently become ...
Costa, A., Pinto, A., Varum, H.
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy