Results 71 to 80 of about 11,825,662 (256)

Improved osteogenic differentiation of umbilical cord blood MSCs using custom made perfusion bioreactor

Biomedical Journal, 2018
Background: 3D cell culture is an appropriate method to develop engineered bone tissue, where different bioreactors have been designed to mitigate the challenges in 3D culture.
Bhaskar Birru, Naveen Kumar Mekala, Sreenivasa Rao Parcha   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Magnetic lab-on-a-chip for cell analysis : magnetoresistive-based real-time monitoring of dynamic cell-environment interactions [PDF]

, 2013
Shoshi A. Magnetic lab-on-a-chip for cell analysis : magnetoresistive-based real-time monitoring of dynamic cell-environment interactions.
Shoshi, Astrit
core  

Bond tilting and sliding friction in a model of cell adhesion

, 2007
As a simple theoretical model of a cell adhering to a biological interface, we consider a rigid cylinder moving in a viscous shear flow near a wall. Adhesion forces arise through intermolecular bonds between receptors on the cell and their ligands on the
Jensen, O. E.; id_orcid, Reboux, S., Richardson, Giles, Jensen, O.E., Richardson, G.   +4 more
core   +1 more source

T-Cell activation: a queuing theory analysis at low agonist density [PDF]

, 2006
We analyze a simple linear triggering model of the T-cell receptor (TCR) within the framework of queuing theory, in which TCRs enter the queue upon full activation and exit by downregulation.
Wedagedera, J.R., Burroughs, N.J., Burroughs, Nigel John, Wedagedera, J. R.   +3 more
core   +1 more source

αII-spectrin in T cells is involved in the regulation of cell-cell contact leading to immunological synapse formation? [PDF]

PLoS ONE, 2017
T-lymphocyte activation after antigen presentation to the T-Cell Receptor (TCR) is a critical step in the development of proper immune responses to infection and inflammation.
Justyna M Meissner, Aleksander F Sikorski, Tomasz Nawara, Jakub Grzesiak, Krzysztof Marycz, Dżamila M Bogusławska, Izabela Michalczyk, Marie-Christine Lecomte, Beata Machnicka   +8 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Dynamic formation of oriented patches in chondrocyte cell cultures [PDF]

, 2010
Growth factors have a significant impact not only on the growth dynamics but also on the phenotype of chondrocytes (Barbero et al. in J. Cell. Phys. 204:830-838, 2005).
Wagner, B., Viviana Palumberi, Marcus J. Grote, Barbara Wagner, Grote, Marcus, Palumberi, V., Palumberi, Viviana, Barbero, Andrea, Barbero, A., Grote, Marcus J., Andrea Barbero, Grote, M. J., Martin, Ivan, Ivan Martin, Martin, I., Wagner, Barbara   +15 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

RhoGDI1 regulates cell-cell junctions in polarized epithelial cells

Frontiers in Cell and Developmental Biology
Cell-cell contact formation of polarized epithelial cells is a multi-step process that involves the co-ordinated activities of Rho family small GTPases. Consistent with the central role of Rho GTPases, a number of Rho guanine nucleotide exchange factors (
Nicolina Wibbe, Tim Steinbacher, Frederik Tellkamp, Frederik Tellkamp, Niklas Beckmann, Frauke Brinkmann, Manuel Stecher, Volker Gerke, Volker Gerke, Carien M. Niessen, Carien M. Niessen, Carien M. Niessen, Klaus Ebnet, Klaus Ebnet   +13 more
doaj   +1 more source