Results 161 to 170 of about 4,592,600 (302)

The Study of Dynamic Characteristic of Acupoints Based on the Primary Dysmenorrhea Patients with the Tenderness Reflection on Diji (SP 8). [PDF]

Evid Based Complement Alternat Med, 2015
Chen S, Miao Y, Nan Y, Wang Y, Zhao Q, He E, Sun Y, Zhao J.   +7 more
europepmc   +1 more source

Multiple Integration on Time Scales

, 2005
In this paper an introduction to integration theory for multivariable functions on time scales is given. Such an integral calculus can be used to develop a theory of partial dynamic equations on time scales in order to unify and extend the usual partial ...
Guseinov, GS, Bohner, M
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The effect of floating spline parameter on the dynamic characteristic of encased differential planetary gear train. [PDF]

Sci Rep
Che X, Yu H, Zhang C, Zhu R.
europepmc   +1 more source

Dynamical systems of characteristic 0⁺ [PDF]

Pacific Journal of Mathematics, 1970
openaire   +2 more sources

Paradigmatic well posedness in some generalized characteristic Cauchy problems [PDF]

By means of convenient regularization for an ill posed Cauchy problem, we deï¬ne an associated generalized problem and discuss the conditions for the solvability of it.
Emmanuel Allaud, Jean-André Marti, Hans Vernaeve, Victor Dévoué, Antoine Delcroix   +4 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Partial Differentiation on Time Scales

, 2004
In this paper a differential calculus for multivariable functions on time scales is presented. Such a calculus can be used to develop a theory of partial dynamic equations on time scales in order to unify and extend the usual partial differential and ...
Guseinov, GS, Bohner, M
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source