Results 61 to 70 of about 3,657,233 (310)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
A fast spraying speed, wide working area, and easy operation are the operational advantages of high-clearance boom sprayers. To address the issue of spray boom mechanical vibration affecting the spraying effect, a double-link trapezoidal boom suspension ...
Changxi Liu +6 more
doaj +1 more source
Dynamic response of the fluid force acting on an axially oscillating balance piston was numerically investigated. The balance piston of a rocket engine turbopump was modeled and forced to oscillate in the axial direction.
Toshiya KIMURA +4 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Combinatorial regulation: characteristics of dynamic correlations
A cis-regulatory module often processes multiple regulatory inputs provided by transcription factors that bind to DNA and regulate the expression of the gene in a combinatorial logic manner. Here the authors analyse dynamic cross correlations between the regulator concentrations and the output of the gene using stochastic modelling, and show their ...
J, Zhang, Z, Yuan, T, Zhou
openaire +2 more sources
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Design and Flow Characteristics of a Gravity-Driven Flow Control Valve
Ultra-high-temperature and pressure downhole environments pose challenges for conventional electronic instruments to adapt to high-temperature formations, thereby restricting the application of downhole electronic tool technology in deep and ultra-deep ...
Qing Wang +11 more
doaj +1 more source
Dynamic structure factor and collective excitations of neutral and Coulomb fluids [PDF]
The dynamic sructure factor as the basic quantity describing the collective excitations in a fluid is considered. We consider the cases of neutral and Coulombic fluids.
Ortner, J.
core +2 more sources
Dynamic Characteristic Identification
This paper introduces a dynamic system parameter extraction approach using experimental data and a known characteristic equation for a single degree of freedom mass-spring-damper system. The efficacy of curve fitting to determine mass, damping, and stiffness for simulated underdamped, critically damped, and overdamped systems is explored.
Clay Jordan, Tommy Hazelwood
openaire +2 more sources

