Results 81 to 90 of about 9,007,074 (305)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Folder 6: Model engine data sheets and operating instructions, J - N, ca. 1960, 1972, 1988

open access: yes, 1960
Instructions, illustrations, and parts price list for a Dynamic Models, INC. Johnson Engines.
Dynamic Models, Inc.
core  

Dynamic research of solar cells / Dinaminis saulės elemento tyrimas

open access: yesMokslas: Lietuvos Ateitis, 2017
Solar cells are one of the most popular renewable energy generation technologies, because they are reliable, low operating and maintenance costs, to conclude without any moving parts and is a boundless source of energy.
Vytautas Makarskas   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

THE PROBLEM OF IMPROVEMENT OF THE AVIONIC EQUIPMENT VIBRATION RESISTANCE

open access: yesНаучный вестник МГТУ ГА, 2017
The article gives an approach to a solution of the problem of improvement the avionic equipment vibration resistance. It is shown that the use of the tests, which are provided by the state standards do not insure the required level of the failures caused
E. A. Danilova   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Contractive self maps of alpha-psi-type on fuzzy metric spaces

open access: yes, 2021
[EN] We introduce and discuss a notion of $\alpha -\psi $-contractive self map for fuzzy metric spaces in the sense of Kramosil and Michalek, which allows us to prove a fixed point theorem that constitutes a fuzzy counterpart of a relevant fixed point ...
Romaguera Bonilla, Salvador   +1 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Bridge roughness index as an indicator of bridge dynamic amplification [PDF]

open access: yes, 2006
The concept of a road roughness index for bridge dynamics is developed. The International Roughness Index (IRI) is shown to be very poorly correlated with bridge dynamic amplification as it takes no account of the location of individual road surface ...
O'Brien, Eugene J.   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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