Results 71 to 80 of about 477 (209)
Several X-ray crystal structures of the E. coli core clamp loader containing the five core (δ′, δ, and three truncated γ) subunits have been determined, but they lack the ψ and χ subunits.
Farzaneh Tondnevis +3 more
doaj +1 more source
The replicative DNA polymerase PolIIIα from Escherichia coli is a uniquely fast and processive enzyme. For its activity it relies on the DNA sliding clamp β, the proofreading exonuclease ε and the C-terminal domain of the clamp loader subunit τ.
Rafael Fernandez-Leiro +3 more
doaj +1 more source
Dynamics of Open DNA Sliding Clamps
A range of enzymes in DNA replication and repair bind to DNA-clamps: torus-shaped proteins that encircle double-stranded DNA and act as mobile tethers. Clamps from viruses (such as gp45 from the T4 bacteriophage) and eukaryotes (PCNAs) are homotrimers, each protomer containing two repeats of the DNA-clamp motif, while bacterial clamps (pol III β) are ...
openaire +5 more sources
A CMOS‐compatible, all‐dielectric Silicon‐on‐Glass reflective metasurface enables low–loss terahertz wavefront control for future 6G wireless communication. Mie‐resonant silicon pillars provide full phase coverage near 500 GHz, achieving experimentally validated single‐, dual‐, and five‐beam steering with sub‐1.5° angular error and less than 3 dB ...
Rithwik Premanand +6 more
wiley +1 more source
Self‐Assembled Lipids as Soft Dielectrics
Self‐assembled lipid bilayers serve as soft dielectric materials for ultrathin electronics. Using liquid‐metal parallel‐plate junctions, the capacitance and dielectric breakdown of dehydrated lipid films are characterized. Dielectric behavior is controlled by lipid molecular structure, cholesterol content, and assembly conditions, providing molecular ...
Hao Yang +4 more
wiley +1 more source
Small size of an axon and presynaptic structures have hindered direct functional analysis of axonal signaling and transmitter release at presynaptic boutons in the central nervous system.
Shin-ya Kawaguchi +2 more
doaj +1 more source
A fully polymeric two‐dimensional array of Dielectric Elastomers enables self‐sensing, cooperative actuation, and large‐stroke operation in a DE‐based autonomous conveyor. Based only on voltage and current measurements at actuator level, the system detects the presence of a ball and subsequently drives it toward a target position.
Saverio Addario +6 more
wiley +1 more source
Thermoresponsive Soft and Self‐Anchoring Cuff Electrode for Chronic Peripheral Interfaces
A novel thermoresponsive, soft and self‐anchoring (TSSA) cuff electrode utilizing shape memory polymers achieves autonomous, sutureless peripheral nerve fixation. Driven by thermally induced pre‐strain and tissue adhesion, the device self‐closes and softens at body temperature, successfully minimizing mechanical mismatch. This adaptive platform ensures
Seungjun Lee +4 more
wiley +1 more source
Local polar frustration is engineered to stabilize an ergodic relaxer through nanoscale multiphase coexistence, suppressing long‐range ferroelectric order while preserving high polarization. This strategy delivers ultrahigh low‐field normalized energy density (Wa >0.020 mC cm−2), exceptional thermal stability, and a transferable design principle for ...
Hareem Zubairi +9 more
wiley +1 more source
HfxZr1−xO2${\rm Hf}_x{\rm Zr}_{1-x}{\rm O}_2$ offers CMOS‐compatible nanoscale ferroelectricity yet suffers from a high Ec${\rm E}_c$ demanding large operating voltages. A unified phase‐field framework spanning AFE/FE/DE phases shows how FE grains soften neighboring AFE grains over λ$\lambda$ ≈$\approx$ 22–37 nm.
P. Pankaj +4 more
wiley +1 more source

