Results 171 to 180 of about 43,950 (246)

Electrically Tunable Piezotronic Transistor by Coupling Interface Polar Symmetry and Strain Gradient

Advanced Science, EarlyView.
A macroscale tip‐induced strain gradient generates bulk piezo‐charges in GaN, enabling bias‐controlled shielding and selective Schottky barrier modulation. This strain‐gradient piezotronic transistor exhibits electrically switchable high‐ and low‐sensitivity states, providing ultrahigh strain sensitivity and wide tunability for adaptive mechanical ...
Gongwei Hu, Xiaoming Dong, Yihan Zhang, Yong Chao, Menglu Li, Min Liu, Liqing Pan, Lijie Li, Wei Huang, Fobao Huang   +9 more
wiley   +1 more source

A Drive-Vibration Integrated Piezoelectric Actuator for Flexible Electrode Implantation. [PDF]

Micromachines (Basel)
Li X, Wu D, Lin X, Jiang T, Ma J, Li Y, Hu Y, Wang Y, Zhong H, Yang X, Li J, Wen J.   +11 more
europepmc   +1 more source

Longitudinal Single‐Axon‐Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant

Advanced Science, EarlyView.
A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky, Emma Anisman, Ron Perez, Sophia Zhang, Morgan Hoffman, Daniel Hunter, Abigail Cherian, Jevon Bonner, Emilia Feria, Ahmed Ahmed, Muneeb Malik, Junwei Du, Leland C. Sudlow, David M. Brogan, Matthew D. Wood, Mikhail Y. Berezin   +15 more
wiley   +1 more source

DynMoCo: A novel AI framework to reveal modular substructures of protein from molecular dynamics. [PDF]

Biophys J
Mao L, Kwak M, Kazemipour Ashkezari AH, Li Z, Cong P, Chen Y, Phee JH, Kang S, Li J, Zhu C.   +9 more
europepmc   +1 more source

Pathological Copper Overload Reprograms SOD1 Activation via COMMD1 to Promote Senescence and Fibrosis

Advanced Science, EarlyView.
This study uncovers a previously unrecognized copper‐COMMD1‐SOD1 regulatory axis, revealing that pathological copper overload paradoxically suppresses SOD1 activity by promoting COMMD1‐dependent disruption of SOD1 homodimerization. These findings redefine the regulatory role of copper in SOD1 biology and provide novel mechanistic insight into the ...
Yuqing Liu, Jing Liu, Wenqian Zhou, Yangyang Niu, Yan Zheng, Yiguo Liu, Yingying Zhang, Chen Yu   +7 more
wiley   +1 more source

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

Advanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan, Chongchong Xu, Jiangmei Gao, Pu Wang, Qingling Wu, Ying Jin, Binyan Lu, Mu Li, Mingting Shao, Bihai Li, Zhenghui Su, Yijng Zhang, Jianhuan Chen, Haojie An, Mengyao Huang, Xiaoji Zhuang, Yuhui Shen, Fenglin Wang, Nana Xu, Yiyan Liu, Lei Tang, Xiuling Zhong, Minyan Zhong, Jiecong Chen, Zhenhuang Wang, Xingrong Luo, Sheng Liu, RuiFeng Liu, Ling Zhang, Junhua Rao   +29 more
wiley   +1 more source

A robotic patch-clamp system with real-time localization and phase-synchronized capture of dynamic in vivo cells using micropipette resistance modelling. [PDF]

Microsyst Nanoeng
Li R, Chen H, Hu B, Qiu J, Liu Y, Guo Z, Wu S, Liu M, Ding R, Ding S, Li Y, Pang X, Shen H, Zhao Q, Zhao X.   +14 more
europepmc   +1 more source

Implementing dynamic clamp with synaptic and artificial conductances in mouse retinal ganglion cells. [PDF]

J Vis Exp, 2013
Huang JY, Stiefel KM, Protti DA.
europepmc   +1 more source

Biomimetic Self‐Reconfigurable Soft Gripper for Cross‐Scale, Multi‐Particle, and High‐Load Multifunctional Manipulation

Advanced Science, EarlyView.
A fully soft, self‐reconfigurable gripper inspired by rapeseed flowers is monolithically 3D‐printed and electronics‐free, switching between diagonal and parallel finger arrangements. Establishing a self‐reconfigurable grasping paradigm, the gripper enables diverse manipulation tasks, including rotating bulbs, picking fruits, grasping cross‐scale ...
Qiping Xu, Bin Wang, Jinxin Chen, Zhengqiang Guo, Baisong Yang, Chaoqian Chen, Jiancheng Cai, Chee‐Meng Chew, Shiju E   +8 more
wiley   +1 more source

Pulse pressure variation versus central venous pressure guided fluid management therapy in kidney transplant recipients: A single-blinded prospective randomized control study. [PDF]

Saudi J Anaesth
Gupta S, Arora D.
europepmc   +1 more source