Results 101 to 110 of about 18,404 (264)

Two Years of Ocrelizumab Treatment in Black and Hispanic People with Multiple Sclerosis in CHIMES: A Single‐Arm Clinical Trial

Annals of Neurology, EarlyView.
Objective To evaluate the effectiveness and safety of ocrelizumab in self‐identified black and Hispanic people with relapsing multiple sclerosis. Methods The Characterization of Ocrelizumab in Minorities with Multiple Sclerosis (CHIMES) trial, a prospective, open‐label, single‐arm, phase 4 study, intentionally recruited underrepresented populations in ...
Lilyana Amezcua, Anthony T. Reder, Evanthia Bernitsas, Nancy L. Monson, Timothy Vartanian, Gregory F. Wu, Mansoor Saleh, Annette Okai, Ahmed Z. Obeidat, Dilraj Sokhi, Rikisha Parekh, Jinglan Pei, Christopher Harp, David Clayton, Ibraheem Abioye, Mitzi J. Williams, for the CHIMES Study Group   +16 more
wiley   +1 more source

Wood Sawdust as a Low‐Cost Filler in Whole‐Tire Reclaimed Rubber: Mechanical Characterization and Factory‐Scale Cost Analysis

Journal of Applied Polymer Science, EarlyView.
Whole‐tire reclaimed rubber is upgraded with wood sawdust, a carpentry by‐product available at no cost, across loadings from 0 to 20 wt%. At 5 wt%, tensile strength, elongation, hardness, viscosity, and water absorption all stay within commercial specification, and real factory data show an annual production saving near $62,000 with no capital ...
Mohammed S. Matar, Faris Tarlochan, Sami E. Alkhatib, Abdullah Abdelhamid   +3 more
wiley   +1 more source

Innervation of the tubarial glands: A hypothesis‐driven anatomical review

The Anatomical Record, EarlyView.
Abstract The tubarial glands have been described as a macroscopic bilateral glandular complex in the posterolateral nasopharynx near the torus tubarius and the pharyngeal opening of the Eustachian tube. Since their recognition on prostate‐specific membrane antigen‐based imaging, their anatomical classification has remained debated, with converging ...
Mugurel Constantin Rusu, Ivan Varga, Răzvan Costin Tudose   +2 more
wiley   +1 more source

Design and Optimization of Double-Tail Dynamic Latch CMOS Comparator With Modified Widlar Current Source

Journal of Electrical and Computer Engineering
The comparator plays a vital role in analog-to-digital converters. In the emerging communication era, these converters are useful to connect the analog field to the digital field.
Tejender Singh, Suman Lata Tripathi
doaj   +1 more source

A 13-Bit 100 kS/s Two-Step Single-Slope ADC for a 64 × 64 Infrared Image Sensor

Eng
An Analog-to-Digital Converter (ADC) is an indispensable part of image sensor systems. This paper presents a silicon-based 13-bit 100 kS/s two-step single-slope analog-to-digital converter (TS-SS ADC) for infrared image sensors with a frame rate of 100 ...
Qiaoying Gan, Wenli Liao, Weiyi Zheng, Enxu Yu, Zhifeng Chen, Chengying Chen   +5 more
doaj   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

The role of editorial boards in shaping scholarly communication: A large‐scale mapping of their composition and structure

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Editorial boards play a central role in shaping scholarly communication by influencing what research is published and how disciplinary boundaries are defined. Despite their importance, large‐scale, systematic evidence on their composition and structure remains limited.
Evangelina Becerra‐Rodero, José Luis Ortega   +1 more
wiley   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Dataset Dynamics Compendium: A Comparative Study [PDF]

, 2010
At the time of writing there exists no consensus about the approaches to detect, propagate and describe changes in resources and datasets of the Linked Open Data Web. This survey gives a comprehensive overview of the current technical solutions and a comparison of such based requirements we derived from use cases the community came up with.
Umbrich, J., Villazón Terrazas, Boris, Hausenblas, M.   +2 more
openaire   +1 more source

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source