Results 51 to 60 of about 18,404 (264)

Bio‐Inspired Biopolymeric Implantable Platform for Localized and Sustained Drug Delivery in Solid Tumor Treatment

open access: yesAdvanced Functional Materials, EarlyView.
A bio‐inspired biopolymeric implantable drug delivery platform enables localized and sustained release of 7‐ethyl‐10‐hydroxycamptothecin (SN‐38) in solid tumor treatment. The three‐dimensional (3D) structured crosslinked‐chitosan implants are fabricated via 3D‐printed molds and provide drug release over 3 months, significantly inhibiting tumor growth ...
Mercedes Lozano‐Garcia   +12 more
wiley   +1 more source

A 12-Bit Low-Input Capacitance SAR ADC With a Rail-to-Rail Comparator

open access: yesIEEE Access, 2023
The input capacitance of the SAR ADC is considered a drawback in many applications. In this paper, a 12-bit low-power SAR ADC with low-input capacitance is proposed. The ADC is based on a separated DAC and sample-and-hold blocks (SB) structure.
Nima Shahpari   +3 more
doaj   +1 more source

Comparator with dynamic hysteresis

open access: yesElectronics Letters, 1999
A comparator is presented which is based on the use of a time domain phenomenon called 'dynamic hysteresis'. This comparator features only one threshold and a short-time controllable noise immunity.
G. Panov, D. Manova, A. Popov
openaire   +1 more source

Biphasic Co‐Delivery of Curcumin and 5‐FU using 3D‐Printed Dissolving Microneedles for Skin Cancer Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Using pixel‐aware digital light processing, the authors created high‐resolution, dissolvable microneedles from a PEGDA/VP matrix. These microneedles encapsulate curcumin and 5‐fluorouracil and dissolve in the skin, co‐delivering drugs directly to tumours.
Rutuja N. Meshram, Dimitrios A. Lamprou
wiley   +1 more source

A low‐offset low‐power and high‐speed dynamic latch comparator with a preamplifier‐enhanced stage

open access: yesIET Circuits, Devices and Systems, 2021
The preamplifier module is a crucial element while designing dynamic latch comparators. The traditional double tail comparator utilizes a differential pair as the preamplifier stage.
Jérôme K. Folla   +6 more
doaj   +1 more source

Multiwavelength Implantable Oximeter for Wireless Monitoring of Tissue Oxygenation in the Presence of Blood Volume Changes

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents an implantable, wireless, battery‐free oximeter that can continuously monitor physiologically consistent regional tissue oxygenation under dynamic changes of blood volume. This is achieved through multiwavelength photoplethysmography and validated both via Monte Carlo simulations and in vivo rat studies. Different stress events were
Anat Usatinsky   +12 more
wiley   +1 more source

A Dynamic Offset Reduction Technique to Mitigate the Effect of Threshold Mismatch in Energy Efficient Comparators

open access: yesIEEE Access
This work proposes an energy-efficient offset reduction technique for dynamic comparators. An additional capacitor and four transistors are used to minimize the effect of threshold mismatch by dynamically sampling the common mode and differential signals.
Bibhudutta Satapathy, Amandeep Kaur
doaj   +1 more source

A 1.15 μW 200 kS/s 10-b Monotonic SAR ADC Using Dual On-Chip Calibrations and Accuracy Enhancement Techniques

open access: yesSensors, 2018
Herein, we present an energy efficient successive-approximation-register (SAR) analog-to-digital converter (ADC) featuring on-chip dual calibration and various accuracy-enhancement techniques.
Jae-Hun Lee   +5 more
doaj   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

open access: yesAdvanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans   +7 more
wiley   +1 more source

Design of Ultra-Low-Power Rail-to-Rail Input Common Mode Range Standard-Cell-Based Comparators

open access: yesJournal of Low Power Electronics and Applications
In this paper, a NOR2 standard-cell-based dynamic comparator providing rail-to-rail input common mode range (ICMR) is presented, together with a novel standard-cell oriented design methodology.
Antonio Manno   +2 more
doaj   +1 more source

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