Results 71 to 80 of about 64,005 (305)

Beyond CD30: Dual‐Targeting of Malignant and Regulatory T Cells by Brentuximab Vedotin Remodels the Lymphoma Microenvironment and Overcomes Resistance via BCL2 Inhibition in Mycosis Fungoides

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA analyses of paired lesions from CD30+ mycosis fungoides patients demonstrate that brentuximab vedotin (BV) induces immunogenic cell death in both CD30+ and CD30− malignant T cells. BV also targets regulatory T cells and remodels tumor microenvironment, while resistance is driven by impaired IFN responses, drug efflux, and BCL2 ...
Yi Jiang   +8 more
wiley   +1 more source

A 12-Bit Low-Input Capacitance SAR ADC With a Rail-to-Rail Comparator

open access: yesIEEE Access, 2023
The input capacitance of the SAR ADC is considered a drawback in many applications. In this paper, a 12-bit low-power SAR ADC with low-input capacitance is proposed. The ADC is based on a separated DAC and sample-and-hold blocks (SB) structure.
Nima Shahpari   +3 more
doaj   +1 more source

Comparing Social Network Dynamic Operators

open access: yesElectronic Proceedings in Theoretical Computer Science, 2023
In Proceedings TARK 2023, arXiv:2307 ...
Baccini, Edoardo, Christoff, Zoé
openaire   +3 more sources

Multi‐Scale Mapping of Gene Expression from Whole‐slide Images for Identifying Phenotype‐Associated Subpopulations

open access: yesAdvanced Science, EarlyView.
BiSCALE: A pathology‐driven deep learning framework for multi‐scale gene expression prediction from whole‐slide images. It accurately infers bulk and near‐cellular spot‐level expression, links predictions to clinical phenotypes, identifies disease‐associated niches, and enables applications in risk stratification and cell‐identity annotation, providing
Hailong Zheng   +8 more
wiley   +1 more source

A low‐offset low‐power and high‐speed dynamic latch comparator with a preamplifier‐enhanced stage

open access: yesIET Circuits, Devices and Systems, 2021
The preamplifier module is a crucial element while designing dynamic latch comparators. The traditional double tail comparator utilizes a differential pair as the preamplifier stage.
Jérôme K. Folla   +6 more
doaj   +1 more source

Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion

open access: yesAdvanced Science, EarlyView.
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang   +8 more
wiley   +1 more source

A Novel Cyclic Time to Digital Converter Based on Triple-Slope Interpolation and Time Amplification [PDF]

open access: yes, 2015
This paper investigates a novel cyclic time-to-digital converter (TDC) which employs triple-slope analog interpolation and time amplification techniques for digitizing the time interval between the rising edges of two input signals(Start and Stop).
Farshidi, E., Rezvanyvardom, M.
core   +2 more sources

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

A Dynamic Offset Reduction Technique to Mitigate the Effect of Threshold Mismatch in Energy Efficient Comparators

open access: yesIEEE Access
This work proposes an energy-efficient offset reduction technique for dynamic comparators. An additional capacitor and four transistors are used to minimize the effect of threshold mismatch by dynamically sampling the common mode and differential signals.
Bibhudutta Satapathy, Amandeep Kaur
doaj   +1 more source

A 1.15 μW 200 kS/s 10-b Monotonic SAR ADC Using Dual On-Chip Calibrations and Accuracy Enhancement Techniques

open access: yesSensors, 2018
Herein, we present an energy efficient successive-approximation-register (SAR) analog-to-digital converter (ADC) featuring on-chip dual calibration and various accuracy-enhancement techniques.
Jae-Hun Lee   +5 more
doaj   +1 more source

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