Results 61 to 70 of about 15,085 (294)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Refined Measures of Dynamic Connectedness based on TVP-VAR [PDF]

open access: yes, 2017
In this study, we propose refined measures of dynamic connectedness based on a TVP-VAR approach, that overcomes certain shortcomings of the connectedness measures introduced originally by Diebold and Yilmaz (2009, 2012, 2014).
Antonakakis, Nikolaos, Gabauer, David
core  

Time-Varying General Dynamic Factor Models and the Measurement of Financial Connectedness [PDF]

open access: yes, 2021
We propose a new time-varying Generalized Dynamic Factor Model for high-dimensional, locally stationary time series. Estimation is based on dynamic principal component analysis jointly with singular VAR estimation, and extends to the locally stationary ...
Soccorsi, Stefano   +7 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Dynamic Connectedness of Green Bond Markets in China and America: A R2 Decomposed Connectedness Approach

open access: yesInternational Journal of Global Economics and Management
This study investigates the connectedness of two key green bond markets: the Shanghai Stock Exchange Green Bond Index (SSEGB) in China and the S&P U.S. Municipal Green Bond Index (SPMGB) in the United States. Using an R2 decomposed connectedness approach, we analyze the distinct dynamics between these indices.
Lei Zhou, Jun Cui
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Food Inflation Examination through the Dynamic Nexus between Olive Oil and Substitutes

open access: yesEconomies
This study provides insights into food inflation by investigating the dynamic interconnectedness of the prices of olive oil, soybean oil, sunflower oil, and palm oil.
Nikolaos A. Kyriazis
doaj   +1 more source

Risk aversion connectedness in developed and emerging equity markets before and after the COVID-19 pandemic

open access: yesHeliyon, 2020
This study investigates the dynamic connectedness across the variance risk premium in international developed and emerging equity markets based on a Bayesian time-varying parameter vector autoregressive methodology.
Athanasios P. Fassas
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Artificial intelligence and clean/dirty energy markets: tail-based pairwise connectedness and portfolio implications

open access: yesFuture Business Journal
This study investigates the return and volatility connectedness between artificial intelligence (AI) stock ETF and each segment of the energy markets, namely clean energy, dirty energy, and WTI oil.
Bechir Raggad, Elie Bouri
doaj   +1 more source

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