Results 61 to 70 of about 2,968,753 (303)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Connectedness needs of external doctoral students

open access: yes, 2013
Institutional concern about attrition rates of doctoral students raises the question of whether these students withdraw from a program due to perceptions of a lack of connectedness to supervisors, peers or for other reasons.
Erwee, Ronel   +2 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

School Connectedness and African American Students: An Examination with Implications for Policy and Teacher Education

open access: yes, 2022
This study examined (1) student perceptions of school connectedness across racial subgroups (African American, white, Hispanic, Asian or Pacific Islander, and Other); (2) the relationships between student perceptions of school connectedness and school ...
Neely, Adrian
core   +1 more source

Social Connectedness and Tourism Demand [PDF]

open access: yes, 2021
This study employs a new measure of social connectedness, based on Facebook friendship links, to investigate the relationship between social networks and tourism demand.
Gavriilidis, Konstantinos
core   +1 more source

The Influence of Financial Stress on Dynamic Connectedness between Fossil Energy Commodities and Green Energy Markets

open access: yesEkonomi, Politika & Finans Araştırmaları Dergisi
This paper aims to examine the impacts of selected stress variables, such as FSI (Financial Stress Index), VIX (Volatility Index), and EPU (Economic Policy Uncertainty), on dynamic connectedness between green markets (stocks and bonds) and fossil energy ...
Dilvin Taşkın   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Tail-risk connectedness between sukuk and conventional bond markets and their determinants: Evidence from a country-level analysis

open access: yesBorsa Istanbul Review
The study investigates the tail-risk spillover between the markets for sukuk and conventional bonds across fifteen countries between 2016 and 2023. First, we estimate a time varying parameter-value at risk (TVP-VAR)-based frequency connectedness model to
Syed Mabruk Billah   +4 more
doaj   +1 more source

Smooth automorphisms and path-connectedness in Borel dynamics

open access: yesIndagationes Mathematicae, 2004
Let $Aut(X,\mathcal{B})$ be the group of all Borel automorphisms of a standard Borel space $(X,\mathcal{B})$. We study topological properties of $Aut(X,\mathcal{B})$ with respect to the uniform and weak topologies, $τ$ and $p$, defined in [Bezuglyi S., Dooley A.H., Kwiatkowski J., Topologies on the group of Borel automorphisms of a standard Borel space,
Bezuglyi, S., Medynets, K.
openaire   +3 more sources

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