Results 81 to 90 of about 2,400,712 (299)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Dynamic Correlations in Disordered Systems: Implications for High-Temperature Superconductivity

Condensed Matter
Liquids and gases are distinct in their extent of dynamic atomic correlations; in gases, atoms are almost uncorrelated, whereas they are strongly correlated in liquids. This distinction applies also to electronic systems.
Takeshi Egami
doaj   +1 more source

The Asian crisis contagion: A dynamic correlation approach analysis [PDF]

Panoeconomicus, 2009
In this paper we are testing for contagion caused by the Thai baht collapse of July 1997. In line with earlier work, shift-contagion is defined as a structural change within the international propagation mechanisms of financial shocks.
Essaadi Essahbi, Jouini Jamel, Khallouli Wajih   +2 more
doaj   +1 more source

Dynamic charge density correlation function in weakly charged polyampholyte globules

, 2000
We study solutions of statistically neutral polyampholyte chains containing a large fraction of neutral monomers. It is known that, even if the quality of the solvent with respect to the neutral monomers is good, a long chain will collapse into a globule.
Eugene Shakhnovich, F. Langouche, G.H. Fredrickson, H.K. Janssen, Hindrik Jan Angerman, J.P. Bouchaud, M. Doi, N.G. van Kampen, P. Debye, P.C. Martin, P.G. DeGennes, P.G. DeGennes, P.G. Higgs, R. Everaers, R. Graham, V. Yamakov, Y. Kantor, Y. Oono   +17 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Dynamic latent variable modelling and fault detection of Tennessee Eastman challenge process [PDF]

, 2016
Dynamic principal component analysis (DPCA) is commonly used for monitoring multivariate processes that evolve in time. However, it is has been argued in the literature that, in a linear dynamic system, DPCA does not extract cross correlation explicitly.
Cao, Yi, Samuel, Raphael
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Examining the dynamic conditional correlation between oil prices and stock prices: Implications for global financial markets and the impact of COVID-19

Afyon Kocatepe Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi
The dynamic structure of the global economy is one of many factors that affect the fluctuations in the global financial markets. COVID-19, like all other epidemics, has been an important period in human history.
Zeynep İlhan Taşkın
doaj   +1 more source

Flexible Bayesian Dynamic Modeling of Correlation and Covariance Matrices

, 2019
Modeling correlation (and covariance) matrices can be challenging due to the positive-definiteness constraint and potential high-dimensionality. Our approach is to decompose the covariance matrix into the correlation and variance matrices and propose a ...
Elias, Gabriel A., Fortin, Norbert J., Holbrook, Andrew, Lan, Shiwei, Ombao, Hernando, Shahbaba, Babak   +5 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source