Results 61 to 70 of about 3,716,472 (288)
Dynamic Covalent Bonds in the Ebselen Class of Antioxidants Probed by X-ray Quantum Crystallography. [PDF]
Dynamic bonds are essential structural ingredients of dynamic covalent chemistry that involve reversible cleavage and formation of bonds. Herein, we explore the electronic characteristics of Se-N bonds in the organo-selenium antioxidant ebselen and its ...
Banoo, Masoumeh +7 more
core +1 more source
Constitutionally selective dynamic covalent nanoparticle assembly [PDF]
, 2022 The future of materials chemistry will be defined by our ability to precisely arrange components that have considerably larger dimensions and more complex compositions than conventional molecular or macromolecular building blocks.
Euan R., Kay +3 more
core +2 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
, 2011 Teaching at Bond has been written specifically for teachers at Bond University. It contains usefule information to induct teachers into their teaching role at Bond University, provide affirmation teaching strategies as a Bond teacher, and help enhance ...
Kinash, Shelley
core +4 more sources
ProceedingsModern polymers are evolving into multifunctional systems with highly sophisticated behavior, often termed “smart” materials due to their ability to respond to specific stimuli [...]
Praveenkumar Pandurangan +3 more
doaj +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
pH Switchable Emulsions Based on Dynamic Covalent Surfactants
, 2017 Dynamic covalent surfactants were designed to prepare pH switchable emulsions. A dynamic covalent bond between nonamphiphilic building blocks (polyethylenimine (PEI) and benzaldehyde (B)) was introduced to form the dynamic covalent surfactant PEI-B.
Gaihuan Ren (3845455) +5 more
core +1 more source
Dynamic Covalent Dextran Hydrogels as Injectable, Self-adjuvating Peptide Vaccine Depots [PDF]
, 2021 Dextran-based hydrogels are promising therapeutic materials for drug delivery, tissue regeneration devices, and cell therapy vectors, due to their high biocompatibility, along with their ability to protect and release active therapeutic agents.
Bowen, Fan +4 more
core +2 more sources
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source