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Functional systems with orthogonal dynamic covalent bonds
This review summarizes the use of orthogonal dynamic covalent bonds to build functional systems. Dynamic covalent bonds are unique because of their dual nature. They can be as labile as non-covalent interactions or as permanent as covalent bonds, depending on conditions.
Wilson, Adam +2 more
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Selective glucocorticoid receptor properties of GSK866 analogs with cysteine reactive warheads [PDF]
Synthetic glucocorticoids (GC) are the mainstay therapy for treatment of acute and chronic inflammatory disorders. Due to the high adverse effects associated with long-term use, GC pharmacology has focused since the nineties on more selective GC ligand ...
Atucha +61 more
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From sequence-defined macromolecules to macromolecular pin codes [PDF]
Dynamic sequence-defined oligomers carrying a chemically written pin code are obtained through a strategy combining multicomponent reactions with the thermoreversible addition of 1,2,4-triazoline-3,5-diones (TADs) to indole substrates.
Badi, Nezha +4 more
core +1 more source
Recent Progress in Polymers with Dynamic Covalent Bonds
AbstractDynamic covalent bonds (DCBs) have attracted huge interest in the past two decades, particularly in polymer materials, due to their reversibility. The introduction of DCBs into polymers often endows the polymers with unprecedented properties such as self‐healing, shape memory, enhanced mechanical strength, and stimuli responsiveness ...
Liqiang Li +4 more
openaire +1 more source
The exploration of novel bio-based functional polymers has high application value and confirms to sustainable development strategies following the increasing shortage of fossil resources.
Yuan Nie +9 more
doaj +1 more source
Supramolecular reactivity in the gas phase: investigating the intrinsic properties of non-covalent complexes [PDF]
The high vacuum inside a mass spectrometer offers unique conditions to broaden our view on the reactivity of supramolecules. Because dynamic exchange processes between complexes are efficiently suppressed, the intrinsic and intramolecular reactivity of ...
Cera, Luca, Schalley, Christoph A.
core +1 more source
Self-healing polymer hydrogel based on dynamic chemical bonds
Polymer hydrogel is a soft material with a three-dimensional network structure that can absorb and retain a large amount of water. Polymer hydrogels have good biocompatibility, mechanical properties and important application value in biomedical and ...
HOU Bing-na +4 more
doaj +1 more source
Responsive materials based on coordination bonds
Responsive materials can respond to different external stimuli by changing their chemical or/and physical properties, thus being useful for various applications such as drug delivery, bioimaging, actuators, and sensors. A common strategy for constructing
Shi‐Yi Chen +3 more
doaj +1 more source
A mixed drug self-delivery system (DSDS) with high drug content (>50%) was developed to regulate pH-triggered drug release, based on two doxorubicin (DOX)-DOX dimmers: D-DOXADH and D-DOXcar conjugated with acid-labile dynamic covalent bonds (hydrazone ...
Jiagen Li +3 more
doaj +1 more source
Carbazole-based Diradicals for Dynamic Covalent Chemistry [PDF]
Dynamic covalent chemistry (DCC) is focused on the creation of structural scaffolds based on chemical components that interact through strong but reversible bonds.
Badía-Domínguez, Irene +8 more
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