Results 51 to 60 of about 135,127 (291)

Poly(thioether) vitrimers via transalkylation of trialkylsulfonium salts [PDF]

open access: yes, 2017
Vitrimers are permanently cross-linked organic polymers that can be reshaped, molded, and recycled without loss of network integrity. Herein, we report poly(thioether) networks, prepared through a straightforward thiol-ene photopolymerization, that can ...
Hendriks, Benjamin   +3 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Carbazole-based biradicaloids as potential building blocks for dynamic covalent chemistry [PDF]

open access: yes, 2018
Pi-conjugated biradical compounds become essential building blocks in DCC (dynamic covalent chemistry).1 This field is based on the creation of structural scaffolds based on chemical components which interact through strong but reversible bonds ...
Ruíz-Delgado, María del Carmen
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Dynamic covalent chemistries of thermosetting polymer for recyclability and intelligent lubrication

open access: yesFriction
Recently, the focus of materials research has shifted toward intelligent materials and structures with customizable properties and stimulus-responsive functions.
Qihua Wang   +6 more
doaj   +1 more source

Crystallization of Covalent Organic Frameworks for Gas Storage Applications

open access: yesMolecules, 2017
Covalent organic frameworks (COFs) have emerged as a new class of crystalline porous materials prepared by integrating organic molecular building blocks into predetermined network structures entirely through strong covalent bonds.
Lijuan Zhu, Yue-Biao Zhang
doaj   +1 more source

Poly(oxime-ester) Vitrimers with Catalyst-Free Bond Exchange. [PDF]

open access: yes, 2019
Vitrimers are network polymers that undergo associative bond exchange reactions in the condensed phase above a threshold temperature, dictated by the exchangeable bonds comprising the vitrimer.
He, Changfei   +4 more
core  

Stimulus-responsive block copolymer nano-objects and hydrogels via dynamic covalent chemistry [PDF]

open access: yes, 2017
Herein we demonstrate that dynamic covalent chemistry can be used to induce reversible morphological transitions in block copolymer nano-objects and hydrogels.
Armes, S.P.   +5 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Construction and modulation of aggregation‐induced emission materials based on dynamic covalent bonds

open access: yesAggregate
The remarkable advantages and promising application potentials of aggregation‐induced emission (AIE) materials have seen significant advancements in recent years. Notably, AIE materials incorporating dynamic covalent bonds (DCBs) have garnered escalating
Mingxin Zheng   +5 more
doaj   +1 more source

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