Results 51 to 60 of about 454,323 (235)

GIS-Based Framework for Integrating Urban Heritage and Lighting Planning

Buildings
This study develops a GIS-based, heritage-sensitive urban lighting framework for Niğde, Türkiye, integrating Sentinel-2 MSI Level-2A imagery (10 m), ASTER DEM, and municipal cadastral data.
Orhun Soydan, Mertkan Fahrettin Tekinalp
doaj   +1 more source

Introducing Adaptive Incremental Dynamic Analysis: A New Tool for Linking Ground Motion Selection and Structural Response Assessment [PDF]

, 2013
Adaptive Incremental Dynamic Analysis (AIDA) is a novel ground motion selection scheme that adaptively changes the ground motion suites at different ground motion intensity levels to match hazardconsistent properties for structural response assessment ...
Baker, Jack W., Lin, Ting
core   +1 more source

Earthquake‐induced landslide scenarios for seismic microzonation. Application to the Accumoli area (Rieti, Italy) [PDF]

, 2019
Scenarios of earthquake-induced landslides are necessary for seismic microzonation (SM) studies since they must be integrated with the mapping of instability areas.
Battaglia, Simona, Della Seta, M., D’Alessandro, F., Esposito, Carlo, Martini, G., Martino, Salvatore, Pallone, F., Troiani, F.   +7 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Improving root cause analysis through the integration of PLM systems with cross supply chain maintenance data [PDF]

, 2015
The purpose of this paper is to demonstrate a system architecture for integrating Product Lifecycle Management (PLM) systems with cross supply chain maintenance information to support root-cause analysis. By integrating product-data from PLM systems with
Broome, S, Madenas, N, Peachey, S, Tiwari, Ashutosh, Turner, Christopher J.   +4 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

A Multidimensional Perspective on Resilience in Later Life: A Systematic Literature Review of Protective Factors and Adaptive Processes in Ageing

Geriatrics
Background: With the global population rapidly aging, resilience has emerged as a critical determinant of healthy aging. While many factors are associated with resilience, a comprehensive synthesis is needed to inform targeted interventions and policy ...
Benjamin A. Jacob, Cameron Walker, Michael O’Sullivan, Paul Rouse, Matthew Parsons   +4 more
doaj   +1 more source

Methods and tools for assessing the vulnerability of forests and people to climate change [PDF]

, 2008
Adaptation is necessary for reducing the impacts of climate change on forests and societies. So far, forests, forest ecosystem services, and forest-dependent people or sectors have not been adequately represented in adaptation studies or policies, even ...
Brockhaus, Maria, Herawati, Hety, Idinoba, Monica, Kanninen, Markku, Locatelli, Bruno   +4 more
core  

Adaptation of an evidence-based cardiovascular health intervention for rural African Americans in the Southeast [PDF]

, 2019
Background: African Americans (AA) living in the southeast United States have the highest prevalence of cardiovascular diseases (CVD) and rural minorities bear a significant burden of co-occurring CVD risk factors.
Bess, Kiana D., Cene, Crystal W., Corbie-Smith, Giselle, Dave, Gaurav, Davis, Kia, Frerichs, Leah, McFarlin, Shirley, Watson, Sable, Wynn, Mysha, Young, Tiffany   +9 more
core   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source