Results 91 to 100 of about 3,584,282 (275)

Differential optimization measurement technique for magnetic gradient tensors in magnet positioning

open access: yesAin Shams Engineering Journal
The magnetic gradient tensor provides more information about the magnetic source in anomaly detection. However, approximation errors inevitably arise from the differential measurement method.
Jinzhe Wang   +9 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Dynamic and distributed adaptation of scalable multimedia content in a context-aware environment [PDF]

open access: yes, 2006
C
Cazoulat, Renaud   +8 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Full-Space Three-Dimensional Holograms Enabled by a Reflection–Transmission Integrated Reconfigurable Metasurface

open access: yesNanomaterials
A metasurface capable of flexibly manipulating electromagnetic waves to realize holograms presents significant potential in millimeter-wave imaging systems and data storage domains.
Rui Feng   +4 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Dynamic Generation of Airy Beam Utilizing the Full-Space Programmable Metasurface

open access: yesApplied Sciences
Airy beams exhibit enormous application potential in the field of optics and microwave owing to their unique self-bending, self-accelerating, and non-diffracting characteristics.
Rui Feng   +5 more
doaj   +1 more source

Bayesian Analysis of the Glacial‐Interglacial Methane Increase Constrained by Stable Isotopes and Earth System Modeling

open access: yesGeophysical Research Letters, 2018
The observed rise in atmospheric methane (CH4) from 375 ppbv during the Last Glacial Maximum (LGM: 21,000 years ago) to 680 ppbv during the late preindustrial era is not well understood.
Peter O. Hopcroft   +2 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Multi-Peak Narrowband Perfect Absorber Based on the Strong Coupling Between Fabry–Perot Mode and SPP Waveguide Mode

open access: yesPhotonics
Plasmonic- or metamaterial-based multi-narrowband perfect absorbers hold significant potential applications in filtering, photodetection, and spectroscopic sensing.
Yusheng Zhai, Weiji He, Qian Chen
doaj   +1 more source

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