Results 181 to 190 of about 12,005,461 (356)

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Dynamic Generation of Airy Beam Utilizing the Full-Space Programmable Metasurface

open access: yesApplied Sciences
Airy beams exhibit enormous application potential in the field of optics and microwave owing to their unique self-bending, self-accelerating, and non-diffracting characteristics.
Rui Feng   +5 more
doaj   +1 more source

Atypical action updating in a dynamic environment associated with adolescent obsessive-compulsive disorder. [PDF]

open access: yesJ Child Psychol Psychiatry, 2022
Marzuki AA   +7 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

A Reactive Environment for Dynamic Volume Control [PDF]

open access: yes, 2012
El-Shimy D, Hermann T, Cooperstock J. A Reactive Environment for Dynamic Volume Control. In: Essl GE, Gillespie B, Gurevich M, O'Modhrain S, eds. Proceedings of the International Conference on New Interfaces for Musical Expression (NIME).
Gillespie, B.   +6 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Research on the use of dynamic geometry software: implications for the classroom [PDF]

open access: yes, 2005
This review examines research that has investigated the use of dynamic geometry software (DGS) in the teaching and learning of mathematics. The research is categorised under three main headings: interacting with the software, designing teaching ...
Jones, Keith
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

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