Results 121 to 130 of about 4,336,710 (302)
New Criteria for Oscillation of Advanced Noncanonical Nonlinear Dynamic Equations [PDF]
In this study, novel criteria are derived to ensure the oscillation of solutions in nonlinear advanced noncanonical dynamic equations. The obtained results are reminiscent of the criteria proposed by Hille and Ohriska for canonical dynamic equations ...
Amir Abdel Menaem +7 more
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Oscillations of dynamic equations on time scales with advanced arguments
, 2016 In this paper, we investigated the oscillatory behaviour of solutions of advanced dynamic equations on time scales. Under the assumption that the tau is non-monotone or nondecreasing, we present new sufficient conditions for the oscillation of first ...
Ozkan, Umut Mutlu, Ocalan, Ozkan
core +1 more source
Dynamic Analysis of a Pendulum Dynamic Automatic Balancer
Shock and Vibration, 2007 The automatic dynamic balancer is a device to reduce the vibration from unbalanced mass of rotors. Instead of considering prevailing ball automatic dynamic balancer, pendulum automatic dynamic balancer is analyzed.
Jin-Seung Sohn +4 more
doaj +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Nonlinear triple-point problems on time scales
Electronic Journal of Differential Equations, 2004 We establish the existence of multiple positive solutions to the nonlinear second-order triple-point boundary-value problem on time scales, $$displaylines{ u^{Delta abla}(t)+h(t)f(t,u(t))=0, cr u(a)=alpha u(b)+delta u^Delta(a),quad eta u(c)+gamma u^Delta(
Douglas R. Anderson
doaj
Parameter identification for gompertz and logistic dynamic equations. [PDF]
PLoS One, 2020 Akın E, Pelen NN, Tiryaki IU, Yalcin F.
europepmc +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
On Complex Dynamics and the Schrodinger Equation
Intellectual ArchiveComplex Ginzburg-Landau equation (CGLE) is a paradigm of complex dynamics that holds for all spatially extended systems near the onset of oscillatory behavior. CGLE applies to a vast array of phenomena ranging from superconductivity and superfluidity, to Bose-Einstein condensation, astrophysics, nonlinear optics and spatiotemporal chaos. In particular,
openaire +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source