Results 111 to 120 of about 4,336,710 (302)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Monotone iterative technique and existence results for fractional functional differential equations

, 2015
This paper is concerned with the existence of positive solutions for boundary value problems of fractional functional differential equations involving the Caputo fractional derivative. The proof is based on the monotone iterative technique.
Deren F.Y., Hamal N.A., Cerdik T.S.
core  

Oscillation theory for a pair of second order dynamic equations with a singular interface

Electronic Journal of Differential Equations, 2008
In this paper we consider a pair of second order dynamic equations defined on the time scale $I = [a,c]cup [sigma(c),b]$. We impose matching interface conditions at the singular interface $c$.
Pallav Kumar Baruah, Dasu Krishna Kiran Vamsi   +1 more
doaj  

Improved Hille-Type and Ohriska-Type Criteria for Half-Linear Third-Order Dynamic Equations

Mathematics
In this paper, we examine the oscillatory behavior of solutions to a class of half-linear third-order dynamic equations with deviating arguments α2(η)ϕδ2α1ηϕδ1uΔ(η)ΔΔ+p(η)ϕδu(g(η))=0, on an arbitrary unbounded-above time scale T, where η∈[η0,∞)T:=[η0 ...
Taher S. Hassan, Mnaouer Kachout, Bassant M. El-Matary, Loredana Florentina Iambor, Ismoil Odinaev, Akbar Ali   +5 more
doaj   +1 more source

Moving Manifolds in Electromagnetic Fields

Frontiers in Physics, 2017
We propose dynamic non-linear equations for moving surfaces in an electromagnetic field. The field is induced by a material body with a boundary of the surface.
David V. Svintradze
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Some Dynamic Equations

, 2003
In this chapter we consider several dynamic equations and present methods on how to solve these equations. Among them are linear equations of higher order, Euler-Cauchy equations of higher order, logistic equations (or Verhulst equations), Bernoulli ...
Bohner, Martin, Elvan Akin-Bohner, Peterson, Allan, Martin Bohner   +3 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

A Newton Collocation Method for Solving Dynamic Bargaining Games [PDF]

We develop and implement a collocation method to solve for an equilibrium in the dynamic legislative bargaining game of Duggan and Kalandrakis (2008). We formulate the collocation equations in a quasi-discrete version of the model, and we show that the ...
John Duggan, Tasos Kalandrakis
core