Results 41 to 50 of about 189,797 (266)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Stieltjes differential equations, i.e. differential equations with usual derivatives replaced by derivatives with respect to given functions (derivators), are useful to model processes which exhibit dead times and/or sudden changes.
Rodrigo López Pouso +1 more
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Hamiltonian Dynamics and the Schrodinger Equation [PDF]
Summary: It is shown that the Schrödinger equation can be derived via a variation on the Hamiltonian methods of classical physics that feature the action function \(S\). This variation consists mainly in treating an ensemble of particles instead of a single one. Moreover, the ensemble probability fluid must move in accordance with the laws of a special
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Dynamics of Nonlinear Wave Equations [PDF]
80pages. This lecture was written for LIASFMA School on Harmonic Analysis and Wave Equations in Fudan universty(2017). arXiv admin note: text overlap with arXiv:1506.00788, arXiv:0710.5934, arXiv:1407.4525, arXiv:1601.01871, arXiv:1301.4835, 1509.03331, arXiv:1010.3799, arXiv:1201.3258, arXiv:0911.4534, arXiv:1411.7905, by other ...
Miao, Changxing, Zheng, Jiqiang
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Parameter-Dependent Dirac Systems on Time Scales
In this study, we consider two generalized Dirac systems on a time scaleand a boundary-value problem with boundary conditions depending on the spectralparameter. We give some sufficient conditions for disconjugacy of the systemsand obtain a formula about
Ahmet Sinan Özkan
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Dynamics of a Rational Difference Equation [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Wan-Tong Li, Lin-Xia Hu, Xiu-Mei Jia
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Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Dynamics of the Schrödinger–Langevin equation [PDF]
Abstract We consider the nonlinear Schrödinger–Langevin equation for both signs of the logarithmic nonlinearity. We explicitly compute the dynamics of Gaussian solutions for large times, which is obtained through the study of a particular nonlinear differential equation of order 2.
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