Results 51 to 60 of about 188,624 (266)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Resolution methods for mathematical models based on differential equations with Stieltjes derivatives

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2019
Stieltjes differential equations, i.e. differential equations with usual derivatives replaced by derivatives with respect to given functions (derivators), are useful to model processes which exhibit dead times and/or sudden changes.
Rodrigo López Pouso   +1 more
doaj   +1 more source

Hamiltonian Dynamics and the Schrodinger Equation [PDF]

open access: yesProgress of Theoretical Physics, 1974
Summary: It is shown that the Schrödinger equation can be derived via a variation on the Hamiltonian methods of classical physics that feature the action function \(S\). This variation consists mainly in treating an ensemble of particles instead of a single one. Moreover, the ensemble probability fluid must move in accordance with the laws of a special
openaire   +2 more sources

Dynamics of Nonlinear Wave Equations [PDF]

open access: yes, 2019
80pages. This lecture was written for LIASFMA School on Harmonic Analysis and Wave Equations in Fudan universty(2017). arXiv admin note: text overlap with arXiv:1506.00788, arXiv:0710.5934, arXiv:1407.4525, arXiv:1601.01871, arXiv:1301.4835, 1509.03331, arXiv:1010.3799, arXiv:1201.3258, arXiv:0911.4534, arXiv:1411.7905, by other ...
Miao, Changxing, Zheng, Jiqiang
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Parameter-Dependent Dirac Systems on Time Scales

open access: yesCumhuriyet Science Journal, 2018
In this study, we consider two generalized Dirac systems on a time scaleand a boundary-value problem with boundary conditions depending on the spectralparameter. We give some sufficient conditions for disconjugacy of the systemsand obtain a formula about
Ahmet Sinan Özkan
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Dynamics of the Schrödinger–Langevin equation [PDF]

open access: yesNonlinearity, 2021
Abstract We consider the nonlinear Schrödinger–Langevin equation for both signs of the logarithmic nonlinearity. We explicitly compute the dynamics of Gaussian solutions for large times, which is obtained through the study of a particular nonlinear differential equation of order 2.
openaire   +4 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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