Results 101 to 110 of about 9,788,285 (346)
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
The DART general equilibrium model: A technical description [PDF]
This paper provides a technical description of the Dynamic Applied Regional Trade (DART) General Equilibrium Model. The DART model is a recursive dynamic, multi-region, multi-sector computable general equilibrium model.
Springer, Katrin
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Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Persistence and Degradation of Bt Toxin in Two Soil Types Under Different Sterilization Regimes
ToxinsWith the large-scale cultivation of transgenic Bacillus thuringiensis (Bt) crops, the Bt toxin released from Bt crops is continuously introduced into the soil.
Yixuan Fan +7 more
doaj +1 more source
The mathematical foundations of dynamic user equilibrium
Transportation Research Part B: Methodological, 2019 This paper is pedagogic in nature, meant to provide researchers a single reference for learning how to apply the emerging literature on differential variational inequalities to the study of dynamic traffic assignment problems that are Cournot-like ...
T. Friesz, Ke Han
semanticscholar +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Equilibrium Exchange Rates in Transition Countries: Evidence from Dynamic Heterogeneous Panel Models [PDF]
We use a dynamic heterogeneous panel model to estimate real equilibrium exchange rates for advanced transition countries. Our method is based on out-of-sample estimations from middle-income and high-income countries, and we use a pooled mean group ...
Korhonen, Iikka, Kim, Byung-Yeon
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Regulation-Driven Symmetry Evolution and Adaptive Stability in Complex Business Systems
SystemsBusiness development unfolds within complex adaptive environments marked by nonlinear interaction, structural asymmetry, and recurrent instability. Sustained performance under such conditions requires regulatory structures that preserve coherence while ...
Yu-Min Wei
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Nash Equilibrium and Robust Stability in Dynamic Games: A Small-Gain Perspective [PDF]
This paper develops a novel methodology to study robust stability properties of Nash equilibrium points in dynamic games. Small-gain techniques in modern mathematical control theory are used for the first time to derive conditions guaranteeing uniqueness
Jiang, Zhong-Ping +2 more
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