Results 111 to 120 of about 9,788,285 (346)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Dynamic Heterogeneous Search-Mutation Structure-Based Equilibrium Optimizer

open access: yesApplied Sciences
Aiming at the issues of population diversity attenuation, insufficient search efficiency, and susceptibility to a local optimum in the equilibrium optimizer (EO), a dynamic heterogeneous search-mutation structure-based equilibrium optimizer (DHSMEO) is ...
Xiangdong Wu   +3 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Analysis of dynamic traffic models and assignments [PDF]

open access: yes, 2007
This paper develops a comprehensive framework for analysing and solving traffic models and assignments in dynamic setting. Traffic models capture the time-varying travel times and flows on a road network and traffic assignments represent the ...
Chow, A.H.F., Andy H. F. Chow
core  

Colin Rowe y el equilibrio dinámico

open access: yesCuadernos de Proyectos Arquitectónicos, 2015
ResumenEn 1944 Gyorgy Kepes publica el que sin duda será su texto más influyente, El lenguaje de la visión. En él Kepes trata de llevar a cabo una guía que explique la gramática y la sintaxis del fenómeno de la visión, y que sirva como herramienta para ...
Pablo López Martín
doaj  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

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