Results 51 to 60 of about 5,413 (299)
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
From Fault Tree to Credit Risk Assessment: A Case Study [PDF]
Reliability has been largely applied to industrial systems in order to study the various possibilities of systems’ failure. The goal is to establish the chain of events leading to any system’s failure, namely the top event.
Hayette GATFAOUI
core +2 more sources
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Dynamic Fault Tree–Markov Model for Rockburst Risk Assessment in Phosphate Mining
Applied SciencesDeep phosphate mining operations face complex, dynamic working conditions characterized by the superimposed disturbances of high temperature, high stress, and high strain.
Lijing Luo +3 more
doaj +1 more source
Engineering Reports, 2021 Station autonomous computer system is the core of the centralized traffic control (CTC) system. The working mode is dual computer hot standby, and its reliability is very important.
Lu Yan +4 more
doaj +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Data-driven approach to machine condition prognosis using least square regression trees
, 2009 Machine fault prognosis techniques have been profoundly considered in the recent time due to their substantial profit for reducing unexpected faults or unscheduled maintenance.
Yang, Bo-Suk, Tran, Van Tung
core +1 more source
Safety analysis for vehicle guidance systems with dynamic fault trees [PDF]
Reliability Engineering & System Safety, 2019 This paper considers the design-phase safety analysis of vehicle guidance systems. The proposed approach constructs dynamic fault trees (DFTs) to model a variety of safety concepts and E/E architectures for drive automation. The fault trees can be used to evaluate various quantitative measures by means of model checking.
Majdi Ghadhab +4 more
openaire +2 more sources
Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows
Advanced Engineering Materials, EarlyView.A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba +5 more
wiley +1 more source