Results 121 to 130 of about 909,603 (328)
Chapter IV. Magneto-Fluid Dynamical Inviscid Flows [PDF]
, 1962 Ken-ichi Kusukawa
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Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
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Data‐driven performance metrics for neural network learning
International Journal of Adaptive Control and Signal Processing, EarlyView., 2023 Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri +2 more
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Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
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Performance and flow dynamics in cross-flow turbines
, 2018 Aquesta tesi doctoral presenta l'estudi que l'autor va realitzar per comprendre l'efecte de l'angle pitch de la pala sobre les interaccions pala-estela que tenen lloc dins el rotor i, per tant, sobre el rendiment d'una turbina de flux creuat amb tres pales rectes.
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Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
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The Dynamics of Capillary Flow
Physical Review, 1921 Penetration of Liquids into Cylindrical Capillaries.---The rate of penetration into a small capillary of radius $r$ is shown to be: $\frac{\mathrm{dl}}{\mathrm{dt}}=\frac{P({r}^{2}+4\ensuremath{\epsilon}r)}{8\ensuremath{\eta}l}$, where $P$ is the driving pressure, $\ensuremath{\epsilon}$ the coefficient of slip and $\ensuremath{\eta}$ the viscosity. By
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Simulating Migration In The Pensim2 Dynamic Microsimulation Model [PDF]
Modelling migration is fundamentally important to maintaining the appropriate population structure in a dynamic microsimulation model. It is particularly important as it is faster changing than other demographic processes such as fertility and mortality ...
Cathal O’Donoghue +2 more
core
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
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Annual Review of Fluid Mechanics, 2000 Lava flows are gravity currents of partially molten rock that cool as they flow, in some cases melting the surface over which they flow but in all cases gradually solidifying until they come to rest. They present a wide range of flow regimes from turbulent channel flows at moderate Reynolds numbers to extremely viscous or plastic, creeping flows, and ...
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