Results 121 to 130 of about 990,723 (349)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Analyzing temporal mobility pattern shifts: Dynamic origin–destination estimation from aggregated mobile phone location data

open access: yesTransportation Research Interdisciplinary Perspectives
Understanding the dynamic shifts in population distribution is crucial for comprehending spatiotemporal mobility patterns and phenomena at the urban scale.
Alvin Noviansyah   +3 more
doaj   +1 more source

Intervertebral Disc‐on‐a‐ChipMF: A New Model for Mouse Disc Culture via Integrating Mechanical Loading and Dynamic Media Flow (Adv. Mater. Technol. 21/2023) [PDF]

open access: bronze, 2023
Wanqing Xie   +14 more
openalex   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Thermal Exposure Risks in the City: Supply and Demand Disparity Between Urban Shade and Pedestrian Flows Using Mobile Signaling Data

open access: yesLand
Extreme heat poses growing health risks in high-density cities, yet static assessments often fail to capture dynamic pedestrian exposure. This study quantifies the supply and demand disparity between urban shade provision and actual pedestrian demand in ...
Wenxin Cai, Fei Yang, Jiawei Yi
doaj   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

open access: yesMolecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

MONETARY RECEIPTS FROM ABROAD TO INDIVIDUALS: EVALUATION METHODS [PDF]

open access: yesEconomy and Sociology, 2017
The commonly used approaches for assessing the volume of foreign currency flows to individualsprovide estimates, which do not entirely reflect the total amount of foreign currency in cash introduced inthe country.
Mihail POISIC
doaj  

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