Results 121 to 130 of about 4,349,168 (285)
A novel method for the 3D dynamic simulation of oil field station process flows
Journal of Petroleum Exploration and Production TechnologyWith accelerating digitalization across various industries, the demand for digital simulation of oilfield surface engineering process flows has increased substantially.
Hanjiang Xiong +4 more
doaj +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Gross capital flows: Dynamics and crises [PDF]
This paper analyzes the behavior of international capital flows by foreign and domestic agents, dubbed gross capital flows, over the business cycle and during financial crises.
Tatiana Didier +3 more
core
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Механика машин, механизмов и материалов, 2014 Features for creation of mathematical models for dynamic calculations of multibody systems on their transitional modes with changing the system states and the direction of power flows are considered.
V.B. Algin
doaj
Urban ScienceUrban spatial structure is foundational for planning and management, yet its dynamic and multi-scale nature remains difficult to capture. Travel-flow networks derived from trajectory data provide a useful lens for revealing intra-urban interactions, but ...
Teqi Dai, Shengyao Qin, Dingdan Zhang
doaj +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
A Decomposition Theorem for Dynamic Flows
CoRRThe famous flow decomposition theorem of Gallai (1985) states that any static edge $s$,$d$-flow in a directed graph can be decomposed into a nonnegative linear combination of incidence vectors of paths and cycles. In this paper, we study the decomposition problem for the setting of dynamic edge $s$,$d$-flows assuming a quite general dynamic flow ...
Lukas Graf 0001 +2 more
openaire +2 more sources
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source