Results 81 to 90 of about 4,060,629 (297)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Loyalty Islands [cartographic material] /
Relief shown by hachures.; Includes map index and declination diagram.; Map series of Loyalty Islands showing grass, wooded and cultivated lands, woodlands, plantation, corals, ridges and peaks, bluffs, roads, trails, marshes, villages, brushes, and ...
United States. Army Air Forces.
core
Modern temporary demountable structures must be designed to withstand the dynamic forces which generated by crowd occupants. The human forces and that cause the dynamic responses of structure have become an important research topic.
Lin He, Jian Yuan, Feng Fan, Cong Liu
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
This study proposed a novel approach for the offline dynamic parameter identification of parallel kinematics mechanisms in which the friction is significant and varying.
Abdur Rosyid, Bashar El-Khasawneh
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
ECLIPSE memorandum number 1: appreciation and outline plan.
Operation 'ECLIPSE' may be put into operation either as the result of a formal signature of the Instrument of Surrender by German Plenipotentiaries or alternatively on the decision of the Supreme Commander after the main portion of the German forces ...
Allied Expeditionary Forces
core
Hydrodynamic response for flexible connectors of mobile offshore base at rough sea states
Mobile offshore base (MOB) was treated as a research object, and a simplified algorithm was developed for determining the dynamic constraint forces on flexible connectors of MOB at rough sea states.
Linjian WU +3 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source

