Results 91 to 100 of about 157,967 (267)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Asymptotic dynamic graph order evolution analysis
Applied Network ScienceIn this work, we investigate the analysis of generators for dynamic graphs, which are defined as graphs whose topology changes over time. We focus on generated graphs whose order (number of nodes) varies over time. We use a concept called “sustainability”
Vincent Bridonneau +2 more
doaj +1 more source
Small Stretch Spanners on Dynamic Graphs
Journal of Graph Algorithms and Applications, 2006 We present fully dynamic algorithms for maintaining 3- and 5-spanners of undirected graphs under a sequence of update operations. For unweighted graphs we maintain a 3-spanner or a 5-spanner under insertions and deletions of edges; on a graph with n ...
Giorgio Ausiello +2 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Threat modelling in Internet of Things (IoT) environments using dynamic attack graphs
Frontiers in the Internet of ThingsThis work presents a threat modelling approach to represent changes to the attack paths through an Internet of Things (IoT) environment when the environment changes dynamically, that is, when new devices are added or removed from the system or when whole
Marwa Salayma
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Influence maximization on temporal networks: a review
Applied Network ScienceInfluence maximization (IM) is an important topic in network science where a small seed set is chosen to maximize the spread of influence on a network.
Eric Yanchenko +2 more
doaj +1 more source
Dynamic Connectivity in Disk Graphs
Discrete & Computational GeometryAbstractLet $$S \subseteq \mathbb {R}^2$$ S ⊆ R 2 be a set of nsites in the plane, so that every site $$s \in S$$
Alexander Baumann +6 more
openaire +6 more sources