Results 81 to 90 of about 157,967 (267)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Summary of Large-Scale Grapb Partitioning Algoritbms
Dianxin kexue, 2014 The large-scale graph partitioning algorithms were summarized and graph computing models in the distributed environment were introduced. Firstly the large-scale static graph partitioning algorithms and the dynamic graph partitioning algorithms were ...
Jinfeng Xu +4 more
doaj
Managing large distributed dynamic graphs for smart city network applications
Applied Network Science, 2019 Smart cities and traffic applications can be modelled by dynamic graphs for which vertices or edges can be added, removed or change their properties. In the smart city or traffic monitoring problem, we wish to detect if a city dynamic graph maintains a ...
Nadav Voloch +2 more
doaj +1 more source
On Subtrees of Fan Graphs, Wheel Graphs, and “Partitions” of Wheel Graphs under Dynamic Evolution
Mathematics, 2019 The number of subtrees, or simply the subtree number, is one of the most studied counting-based graph invariants that has applications in many interdisciplinary fields such as phylogenetic reconstruction.
Yu Yang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Frontiers in Human NeuroscienceIntroductionVoxel hierarchy on dynamic brain graphs is produced by k-core percolation on functional dynamic amplitude correlation of resting-state fMRI.MethodsDirected graphs and their afferent/efferent capacities are produced by Markov modeling of the ...
Dong Soo Lee +9 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Learning temporal attention in dynamic graphs with bilinear interactions. [PDF]
PLoS One, 2021 Knyazev B, Augusta C, Taylor GW.
europepmc +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source