The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
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Real-Time Temperature Effects on Dynamic Impact Mechanical Properties of Hybrid Fiber-Reinforced High-Performance Concrete. [PDF]
Materials (Basel)Huang P +5 more
europepmc +1 more source
Long-Exposure RGB Photography with a Fixed Stand for the Measurement of a Trajectory of a Dynamic Impact Device in Real Scale. [PDF]
Sensors (Basel), 2021 Kovanič Ľ +6 more
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USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
IMPACT: Health and Welfare Division: report 2002-2003.
, 2003 The Government published its ten-year health strategy, Quality and fairness: A health system for you, in November 2001. It contained ambitious targets to improve services and reduce inequalities with far-reaching proposals on everything from bed ...
IMPACT
core
Health system resilience: quantifying the dynamic impact of environmental shocks on health service utilization using an interrupted time series and time-series forecasting approach in Western Province, Zambia. [PDF]
J Clim Chang HealthChiarot CB +7 more
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The Dynamic Impact of Natural Resource Rents, Financial Development, and Technological Innovations on Environmental Quality: Empirical Evidence from BRI Economies. [PDF]
Int J Environ Res Public Health, 2021 Zuo S, Zhu M, Xu Z, Oláh J, Lakner Z.
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Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
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Dynamic impact of E-WOM and green discourse on green hotel supply chain performance with time lag effect. [PDF]
PLoS OneHao L, Lin B, Zhu Y.
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Dynamic Impact Surface Damage Analysis of 3D Woven Para-Aramid Armour Panels Using NDI Technique. [PDF]
Polymers (Basel), 2021 Abtew MA, Boussu F, Bruniaux P, Hong Y.
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