Results 131 to 140 of about 358,015 (308)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

A compressible mixture model with phase transition [PDF]

open access: yes, 2013
We introduce a new thermodynamically consistent diffuse interface model of Allen--Cahn/Navier--Stokes type for multi-component flows with phase transitions and chemical reactions.
Giesselmann, Jan   +2 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

MELGYM: A dynamic control interface for MELCOR simulations

open access: yesSoftwareX
MELCOR is a computer code for the simulation and safety analysis of nuclear facilities, comprising several modules for the calculation of thermal–hydraulic phenomena and aerosol physics.
Antonio Manjavacas   +4 more
doaj   +1 more source

Shaping the Dynamics of a Bidirectional Neural Interface

open access: yesPLoS Computational Biology, 2012
Progress in decoding neural signals has enabled the development of interfaces that translate cortical brain activities into commands for operating robotic arms and other devices. The electrical stimulation of sensory areas provides a means to create artificial sensory information about the state of a device.
Jörn Diedrichsen   +7 more
openaire   +4 more sources

Dynamic user interface for semantic queries. [PDF]

open access: yes, 2012
Increasing popularity of Semantic Web raises a question how we could make a simple user interface for building semantic queries while keeping high precision of results returned.
Spudys, Kęstutis,
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

CIRCLING INTERFACE: AN ALTERNATIVE INTERACTION METHOD FOR ON-SCREEN OBJECT MANIPULATION [PDF]

open access: yes, 2013
An alternative interaction method, called the circling interface, was developed and evaluated for individuals with disabilities who find it difficult or impossible to consistently and efficiently perform pointing operations involving the left and right ...
Ka, Hyun
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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