Results 111 to 120 of about 358,015 (308)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Intelligent Assistant with Artificial Intelligence for Language Learning

open access: yesApplied Sciences
An intelligent assistant with artificial intelligence (AI) for language learning was developed. A dynamic user interface and a supervised feedback module using web technologies (HTML5, CSS3, and JavaScript ES6+) and Python v3.9 for supporting language ...
Diego De-La-Cruz-Salcedo   +4 more
doaj   +1 more source

Dynamic stress analysis of the interface in a particle-reinforced composite [PDF]

open access: yes, 2000
The analysis of the dynamic stress on the particle-matrix interface in particle-reinforced composite for the reason that this stress may lead to the microvoids' nucleation due to the interfacial debonding were studied.
陈建康   +3 more
core  

High speed dynamic clamp interface [PDF]

open access: yes, 2015
The dynamic-clamp technique is highly useful for mimicking synaptic or voltage-gated conductances. However, its use remains rare in part because there are few systems, and they can be expensive and difficult for less-experienced programmers to implement.
Yang, Y.   +4 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Dynamic growth of an interfacial crack between the two anisotropic materials [PDF]

open access: yesFME Transactions, 2014
In this paper is considered behavior of the stress field around the tip of a crack that propagates dynamically along the interface between the two anisotropic materials.
Đoković Jelena M.   +3 more
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Dynamic Healthcare Interface for Patients

open access: yesProcedia Computer Science, 2015
AbstractCanadian healthcare is a fundamental part of society. Challenges such as the aging baby boomer generation require the healthcare industry to meet higher demands while using fewer resources. Computer systems designed to record and report physical health properties of an individual personcan be used in part to accomplish this task. In this paper,
Elhadi M. Shakshuki   +2 more
openaire   +1 more source

Incorporation of a language model into a Brain Computer Interface based speller through HMMs [PDF]

open access: yes, 2012
Brain computer interface (BCI) research deals with the problem of establishing direct communication pathways between the brain and external devices. The primary motivation is to enable patients with limited or no muscular control to use external devices ...
Çetin, Müjdat, Ulaş, Çağdaş
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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