Results 31 to 40 of about 1,355,767 (260)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Mechanism continuously measures static and dynamic cable loads [PDF]
, 1966 Pulley mechanism measures the tensile loads on a cable under static and dynamic conditions, without disturbing the continuity of operation of the system.
core +1 more source
Dynamically Loading Mobile/Cloud Assemblies [PDF]
, 2017 Distributed applications that span mobile devices, computing clusters, and cloud services, require robust and flexible mechanisms for dynamically loading code. This paper describes lady: a system that augments the .net platform with a highly reliable mechanism for resolving and loading assemblies, and arranges for safe execution of partially trusted ...
Pettersen, Robert +3 more
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
On dynamic loads in parallel shaft transmissions. 2: Parameter study [PDF]
Solutions to the governing equations of a spur gear transmission model, developed in NASA TM-100180 (AVSCOM TM-87-C-2), are presented. Factors affecting the dynamic load are identified.
Coy, John J. +2 more
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Perception of Lower Extremity Loads in Stroke Survivors [PDF]
, 2015 Objective: This study aimed to improve our understanding of static and dynamic lower extremity sensory perception and the impact of sensory impairments on the control of walking in stroke survivors. Methods: Using a custom, real-time unloading system, we
Chu, Virginia W. +2 more
core +1 more source
A Soft Computing Approach to Dynamic Load Balancing in 3GPP LTE [PDF]
, 2012 A major objective of the 3GPP LTE standard is the provision of high-speed data services. These services must be guaranteed under varying radio propagation conditions, to stochastically distributed mobile users.
Atayero, A. A., Luka, M. K.
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Dynamic Load and Storage Integration [PDF]
Modern technology combined with the desire to minimize the size and weight of a ship’s power system are leading to renewed interest in more electric or all electric ships.
Davey, K. +6 more
core