Results 61 to 70 of about 280,732 (268)

Calculation of Loads on Carrying Structures of Articulated Circular-Tube Wagons Equipped with New Draft Gear Concepts

open access: yesApplied Sciences, 2020
This article deals with the dynamic load and strength of the carrying structures of articulated circular-tube wagons. The study was conducted on the carrying structures of wagons equipped with new draft gear concepts.
Alyona Lovska   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Enhancing Weigh-in-Motion Systems Accuracy by Considering Camera-Captured Wheel Oscillations

open access: yesSensors
Weigh-in-motion (WIM) systems aim to estimate a vehicle’s weight by measuring static wheel loads as it passes at highway speed over roadway-embedded sensors.
Moritz P. M. Hagmanns   +3 more
doaj   +1 more source

Numerical and experimental study of the dynamic factor of the dynamic load on the urban railway

open access: yesJournal of the Mechanical Behavior of Materials, 2020
This paper presents simulation calculations and experimental measurements to determine the dynamic load factor (DLF) of train on the urban railway in Vietnam. Simulation calculations are performed by SIMPACK software. Dynamic measurement experiments were
Anh Dung Tran   +5 more
doaj   +1 more source

Dynamic Loadings Of Precastretaining Walls

open access: yesKirkuk University Journal-Scientific Studies, 2007
The research aims for the selection of a suitable retaining wall amongst two types of precast concrete walls under dynamic loads (wave pressure). The first wall is of a triangular cross section and has the dimensions (3)m (in height) by (2.2) m (in width) by (0.25-0.3) m (in thickness) and the width of piece (1.44) m. The second wall has dimensions of (
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Numerical Modeling on the Fracturing and Energy Evolution of Large Deep Underground Openings Subjected to Dynamic Disturbance

open access: yesEnergies, 2020
The exploitation of deep resources is necessary for human development. At the same time, high-stress environments that are deep underground bring about great challenges vis-à-vis resource exploitation.
Chun Yang   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Experimental investigation of dynamic soil properties for modeling energy-absorbing layers

open access: yesOpen Engineering
Modeling the propagation of waves in geomechanics is an essential part of dynamic analysis. In geotechnics, the study of the interaction between the soil and the foundation is particularly interesting.
Abood Ahmed Salah   +2 more
doaj   +1 more source

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