Results 191 to 200 of about 122,033 (316)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
A time-dependent reliability model for spatial intermittent motion mechanisms via constant-amplitude alternating fatigue load equivalent method. [PDF]
Cheng P, Zhang T, Zhu Y.
europepmc +1 more source
Evaluation of optimum amount of load shedding to prevent dynamic voltage instability in a longitudinal ac power transmission system [PDF]
Goutam Kumar Panda, A. Chakrabarti
openalex
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer +5 more
wiley +1 more source
Dynamic simulation and intelligent control technology for cutting head load of coal mine roadheader. [PDF]
Feng J, Zhang Y, He Y, Tian M.
europepmc +1 more source
Dynamic Load Carrying Capacity of Flexible Manipulators Using Finite Element Method and Pontryagin’s Minimum Principle [PDF]
Habibnejad Korayem Moharam +2 more
openalex
Dynamic Shear Modulus of Frozen Soil under Repeated Cyclic Loading
Qiong Wang, Qionglin Li
openalex +1 more source
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg +20 more
wiley +1 more source

