Results 171 to 180 of about 137,150 (318)
Research related to vibrations from high speed railway traffic
, 2008 We discuss here recent results from several research programmes related to dynamic aspects and vibrations induced by high speed railway traffic, developed at the computational mechanics group, within the “Escuela de Ingenieros de Caminos” of the ...
Gabaldón Castillo, Felipe +1 more
core
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Experimental determination of dynamic allowance for traffic loading in bridges
, 2012 Transportation Research Board 89th Annual Meeting, Washington DC, 2010-1-10 to 2010-1-14Bridge codes adopt values for dynamic allowance in traffic load models that are necessarily conservative to cover for an entire range of bridges with different ...
O\u27Brien, Eugene J. +4 more
core
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
, 2012 In this paper, an approach to solve mechanical problems with moving loads and flexible bodies is presented. Therefore, the multi-disciplinary modeling language Modelica together with the DLR FlexibleBodies Library is utilized.
Hartweg, Stefan, Heckmann, Andreas
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Structural performance evaluation of electric vehicle chassis under static and dynamic loads. [PDF]
Sci RepZamzam O +4 more
europepmc +1 more source
A Metaheuristic for the Pickup and Delivery Problem with Split-Loads and its Extension
, 2009 In this dissertation, we study improvements in the Pickup and Delivery Problem that can be achieved by allowing multiple vehicle trips to serve a common load.
Dai Yao, YAO, Dai
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source