Results 151 to 160 of about 137,150 (318)
Lubricated contact analysis of a spur gear pair with dynamic loads [PDF]
In the present research study, a comprehensive spur gear lubrication analysis has been carried out to understand the gear contact behaviour under lubrication conditions.
Liu, Huaiju
core
Modelling the vehicle in vehicle-infrastructure dynamic interaction studies
This paper presents the equations of motion for a general articulated road vehicle, with variable numbers of wheels for the tractor and trailer. The equations are applicable to vehicle-bridge dynamic interaction problems for two and three dimensional ...
O\u27Brien, Eugene J. +3 more
core +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The static strength theory applied in the design process of the planetary reducer can’t reflect the dynamic loads suffered by it,so the faults of the planetary reducer are more than the imagination in running process.In order to solve the problem ...
杜秀菊, 王兴贵
doaj
Spur gear lubrication analysis with dynamic loads
A thermal elastohydrodynamic lubrication line contact model, which could handle ultra-thin-film conditions, was developed to study effects of speed on the lubrication performance of a spur gear pair.
Zhu, Caichao +5 more
core +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Microstructure Evolution of 316L Steel Prepared with the Use of Additive and Conventional Methods and Subjected to Dynamic Loads: A Comparative Study. [PDF]
Ziętala M +3 more
europepmc +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The research of deformation characteristics of the rubber reinforced support parts (RRBP), which compensate static and dynamic loadings of elements of bridge constructions, is conducted.
O. I. Skokov +3 more
doaj

