Results 141 to 150 of about 610,012 (310)
Applied SciencesUltra-shallow prefabricated underpass tunnel technology has been widely adopted in urban transportation construction owing to its advantages of rapid construction and minimal environmental impact.
Zhiyi Jin, Yongxu Jia, Tong Han, Ning Xu
doaj +1 more source
Summary of Voyager Design and Flight Loads [PDF]
Estimates of flight loads for Voyager 1 and Voyager 2 are summarized and compared to the Voyager design loads obtained from the shock spectra/impedance method and to the loads obtained using space vehicle transient loads analysis.
Chen, J. C. +2 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Evaluation of MOSTAS computer code for predicting dynamic loads in two bladed wind turbines [PDF]
Calculated dynamic blade loads were compared with measured loads over a range of yaw stiffnesses of the DOE/NASA Mod-O wind turbine to evaluate the performance of two versions of the MOSTAS computer code.
Janetzke, D. C. +2 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Compression-Induced Tensile Mechanical Behaviors of the Crystalline Rock under Dynamic Loads. [PDF]
Materials (Basel), 2020 Zheng B, Qi S, Huang X, Liang N, Guo S.
europepmc +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Experimental evaluation of small-scale erectable truss hardware [PDF]
To aid in the prediction of the dynamic behavior of the space station, a one-tenth scale dynamic test model is to be constructed of commercially available, small scale truss hardware.
Lake, Mark S., Mcgowan, David M.
core +1 more source