Results 41 to 50 of about 122,033 (316)

Modelling of elastoviscoplastic properties of the subgrade. Problem statement 1

Вестник Научно-исследовательского института железнодорожного транспорта, 2016
A brief analysis of the physical and mechanical properties of materials, used in the construction of the rail bed, has shown that in scientific and technical literature there is scattered unsystematic information obtained under different physical ...
V. M. Bel’Kov
doaj   +1 more source

Numerical Analysis of Machine Foundation Resting Saturated Sandy Soil [PDF]

Engineering and Technology Journal, 2014
The behavior of machine foundation on saturated porous medium can be considered as a complicated geotechnical problem due to nature of dynamic loads and plasticity of soil which make the analysis and design of foundation subjected to dynamic loads more ...
Mohammed Y. Fattah, Nahla M. Salim, Wourood T. Al-Shammary   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Modelling of elastoviscoplastic properties of the subgrade. Problem statement 2

Вестник Научно-исследовательского института железнодорожного транспорта, 2017
Research of railway embankments in terms of physical and chemical mechanics were conducted discretely, without the creation of a coherent model of stability of layered systems, taking into account all the determining factors.
V. M. Bel’Kov
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

The Influence of Constructive and Technological Parameters on Dynamic Loads in Elements of a Planetary Mill with a Belt Drive

Механика машин, механизмов и материалов, 2017
The issues associated with determination of dynamic loads encountered in moving the nodes of the planetary mill with a belt drive are considered. The analysis of the influence of constructive and technological parameters on their size is carried out. For
P.E. Vaitekhovich, G.M. Khves’ko, D.N. Borovskiy, E.O. Ilyashenko   +3 more
doaj  

Analysis of Distributed Dynamic Loads Induced by the Own Mass of Manipulator Links and Their Visualization on Interactive 3D Computer Models

Robotics
This study proposes an approach to 3D modeling of spatial manipulators in the Maple 2023 software environment. Algorithms and program codes have been developed to create computer 3D models of manipulators controlled by generalized coordinates.
Muratulla Utenov, Tarek Sobh, Yerbol Temirbekov, Saltanat Zhilkibayeva, Sarosh Patel, Dauren Baltabay, Zhadyra Zhumasheva   +6 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Employing finite element analysis for assessing the condition monitoring of sandwich beams [PDF]

MATEC Web of Conferences
In engineering and transportation, beams are frequently utilized as structural elements for both static and dynamic loads. This paper focuses on a smart structure method that incorporates ANSYS software for modeling and simulation.
Asif Kattimani Mohammed, Khasge Prashant, Mohrir Sheshikanth, Suman Sai, Masum Habib   +4 more
doaj   +1 more source