Results 101 to 110 of about 1,392,897 (308)

Surface and thermomechanical characterization of polyurethane networks based on poly(dimethylsiloxane) and hyperbranched polyester

open access: yeseXPRESS Polymer Letters, 2013
Two series of polyurethane (PU) networks based on Boltorn® hyperbranched polyester (HBP) and hydroxyethoxy propyl terminated poly(dimethylsiloxane) (EO-PDMS) or hydroxy propyl terminated poly(dimethylsiloxane) (HPPDMS), were synthesized.
M. V. Pergal   +6 more
doaj   +1 more source

On damping created by heterogeneous yielding in the numerical analysis of nonlinear reinforced concrete frame elements

open access: yes, 2015
In the dynamic analysis of structural engineering systems, it is common practice to introduce damping models to reproduce experimentally observed features.
Cottereau, Régis, Jehel, Pierre
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Platonic crystal with low-frequency locally resonant snail structures. Wave trapping, transmission amplification and shielding

open access: yes, 2018
We propose a new type of platonic crystal. The proposed microstructured plate includes snail resonators with low-frequency resonant vibrations. The particular dynamic effect of the resonators are highlighted by a comparative analysis of dispersion ...
Brun, M., Carta, G., Morvaridi, M.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Synergistic enhancement of hydrophobic dental adhesives: autonomous strengthening, polymerization kinetics, and hydrolytic resistance

open access: yesFrontiers in Dental Medicine
The leading cause of composite restoration failure is recurrent marginal decay. The margin between the composite and tooth is initially sealed by a low-viscosity adhesive, but chemical, physical, and mechanical stresses work synergistically and ...
Burak Korkmaz   +11 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Dynamic and Sensitivity Analysis General Non-Conservative Asymmetric Mechanical Systems

open access: yesJournal of Mechanical Engineering, 2018
In this paper the concept of generalized form of proportional damping is proposed. Classical modal analysis of non-conservative continua is extended to multi DOF linear dynamic systems with asymmetric matrices.
Žmindák Milan
doaj   +1 more source

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