Results 111 to 120 of about 21,449,468 (299)

Synergistic enhancement of hydrophobic dental adhesives: autonomous strengthening, polymerization kinetics, and hydrolytic resistance

open access: yesFrontiers in Dental Medicine
The leading cause of composite restoration failure is recurrent marginal decay. The margin between the composite and tooth is initially sealed by a low-viscosity adhesive, but chemical, physical, and mechanical stresses work synergistically and ...
Burak Korkmaz   +11 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

A proteomic analysis of engineered tendon formation under dynamic mechanical loading in vitro

open access: yes, 2011
A proteomic analysis of engineered tendon formation under dynamic mechanical loading in vitroPrevious studies have demonstrated the beneficial effect of mechanical loading on in vitro tendon engineering.
Liu, Hongwei   +12 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Dependence of Piezoresistivity of Elastomer/Nanostructured Carbon Composites on Dynamic Mechanical Load Frequency

open access: yes
The aim of this article is to determine piezoresistive sensitivity of elastomer nanostructured carbon composites at dynamic loading tests and show the piezoresistive effect correlations to various frequencies of applied mechanical force in a manner that ...
Knite, Māris   +2 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Composites of Poly(ethylene glycol) and Hydroxyapatite: Dynamic Mechanical Study of the Modulus of Elasticity under Cryogenic Conditions

open access: yesBioResources
The cryogenic mechanical behavior of polyethylene glycol (PEG) and hydroxyapatite (HAp) composites was studied using Dynamic Mechanical Analysis (DMA). The HAp was synthesized from chicken eggshells via a hydrothermal process, offering a sustainable, bio-
Nur Aini Fauziyah   +5 more
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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