Results 131 to 140 of about 1,392,897 (308)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Static and dynamic behaviour of ultra high molecular weight poly-ethylene (UHMWPE) Tensylon® composite

eXPRESS Polymer Letters
Nowadays, ultra high molecular weight polyethylene (UHMWPE), allows the combination of lightweight, high strength and is praised for the design of severely loaded structures. It has become a good option for lightweight armour solutions.
Magali Castres, Aboulghit El Malki Alaoui, Camille Caisso, Martin Monloubou, Michel Arrigoni   +4 more
doaj   +1 more source

Dynamic Mechanical Analysis and Thermal Expansion of Lignin-Based Biopolymers. [PDF]

Polymers (Basel), 2021
Mazurchevici SN, Vaideanu D, Rapp D, Varganici CD, Cărăușu C, Boca M, Nedelcu D.   +6 more
europepmc   +1 more source

Merging of the alpha and beta relaxations and aging via the Johari–Goldstein modes in rapidly quenched metallic glasses [PDF]

, 2008
This paper provides evidence that the physical aging of deeply and rapidly quenched metallic glasses is promoted by the Johari–Goldstein slow beta relaxation, resulting in a significant irreversible increase in the mechanical modulus on initial heating ...
Bedorf, Dennis, Demetriou, Marios D., Hachenberg, Jörg, Johnson, William L., Kahl, Annelen, Richert, Ranko, Samwer, Konrad   +6 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Heat Treatment and Dynamic Mechanical Analysis Strain Sweep Effects on the Phase Structure and Morphology of an Fe-28Mn-6Si-5Cr Shape Memory Alloy. [PDF]

Nanomaterials (Basel), 2023
Popa M, Popa F, Pricop B, Cimpoeșu N, Lohan NM, Kicsi G, Istrate B, Bujoreanu LG.   +7 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Evaluation of Effective Crosslinking Density for Pseudo-Semi Interpenetrating Polymer Networks Based on Polyether Glycols Mixture by Dynamic Mechanical Analysis. [PDF]

Polymers (Basel), 2023
Li Y, Sun B, Liu Y, Zhang Z, Shen Y, Wang H, Liu X, Xie W.   +7 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Dynamic Mechanical Analysis of Thermally Aged Fique Fabric-Reinforced Epoxy Composites. [PDF]

Polymers (Basel), 2021
Oliveira MS, da Luz FS, da Costa Garcia Filho F, Pereira AC, de Oliveira Aguiar V, Lopera HAC, Monteiro SN.   +6 more
europepmc   +1 more source