Results 141 to 150 of about 1,392,897 (308)

The Effect of Injection Moulding Temperature on PET Particles/Fibrils in Blends and MFCs [PDF]

open access: yes, 2016
The microfibrillar composites of polypropylene (PP)/poly(ethylene terephthalate) (PET) have been prepared by twin-screw extrusion, followed by cold drawing. The employed stretch ratio was 4.
Cardon, Ludwig   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Filament Extrusion‐Based Conductive TPU Composite Scaffolds Enable Superior Neuronal Growth and Synaptic Maturation In Vitro

open access: yesEngineering in Life Sciences
Fused filament fabrication (FFF) three‐dimensional (3D) printing technologies offer new opportunities for fabricating customizable, low‐cost platforms for tissue engineering applications.
Kamil Elkhoury   +7 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Enhanced Thermal and Flexural Properties of Alkalized Date Palm/Kenaf Fiber-Reinforced Epoxy Hybrid Composites: A Comparative Study of Untreated and Treated Fibers

open access: yesJournal of Natural Fibers
This study evaluates the thermal and mechanical behavior of hybrid composites made from date palm (DP) and kenaf fibers (KF) in an epoxy thermoset matrix. Both DP and KF fibers are abundant and renewable, reducing environmental impact.
Syed Waheedullah Ghori   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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