Results 61 to 70 of about 1,392,897 (308)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A new method to predict optimum cure time of rubber compound using dynamic mechanical analysis [PDF]
The degree of vulcanization of a rubber compound has a big influence on the properties of the final product. Therefore, precisely defining the curing process including optimum cure time is important to ensure the production of final products having high ...
Aggarwal +15 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Alternating copolyesteramides based on mixtures of 1,4-butyleneterephthalamide and -isophthalamide and ethanediol (4NT/I2) [PDF]
Alternating copolyesteramides (APEA's) consisting of mixtures of 1,4-butyleneterephthalamide ester (N,N′-bis(p-carbomethoxybenzoyl) diaminobutane) and 1,4-butyleneisophthalamide ester (N,N′-bis(m-carbomethoxybenzoyl) diaminobutane) polymerized with ...
Bouma, K. +2 more
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Nanoindentation of bone: Comparison of specimens tested in liquid and embedded in polymethylmethacrylate [PDF]
Elastic modulus of bone was investigated by nanoindentation using common methods of sample preparation, data collection, and analysis, and compared to dynamic mechanical analysis (DMA: three-point bending) for the same samples. Nanoindentation (Berkovich,
Boyde, A, Bushby, AJ, Ferguson, VL
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
A Polymer Optical Fiber Temperature Sensor Based on Material Features
This paper presents a polymer optical fiber (POF)-based temperature sensor. The operation principle of the sensor is the variation in the POF mechanical properties with the temperature variation. Such mechanical property variation leads to a variation in
Arnaldo Leal-Junior +3 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

