Results 41 to 50 of about 112,327 (261)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This paper presents numerical analysis concerning a rubber-concrete composite which can be considered as a structural element designed to form walls. Structural elements that carry the compressive load have a rubber with a specific shape embedded during ...
Izabela Major +2 more
doaj +1 more source
Polymeric materials used for the polymer bonded explosive (PBX) or other energetic composite materials (ECMs) that simultaneously possess excellent mechanical properties and high self-healing ability, convenient healing, and facile fabrication are always
Yu-bin Li +7 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Bond method is widely used in the design of grinding circuits in an ore preparation plant, sizing of mills, determining power requirements and determining and measuring performance, and for materials considered to be comminution.
Yakup Umucu, Yaşar Hakan Gürsoy
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
DEVELOPMENT IN RESEARCH ON THE MECHANICAL PROPERTY OF ADHESIVE JOINTS
The need to design lightweight structures and the increased use of lightweight materials in industrial field,has led to wide use of adhesive bonding. In order to improve the mechanical strength and reliability of adhesive joints,the research results of ...
WANG YuQi, HE XiaoCong, ZENG Kai
doaj
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The effect of silica modified by silane coupling agent (TESPT) and deep eutectic solvent (DES) on the properties of natural rubber (NR) composites as tread rubber was studied.
YANG Hao; WANG Chen-lu; WU Shu-yan; DU Ai-hua
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

