Results 61 to 70 of about 112,327 (261)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Experimental Study of the Dynamic Compressive and Tensile Anisotropic Mechanical Properties and Failure Modes of Shale

open access: yesSensors
To investigate the dynamic compressive and tensile mechanical properties and failure modes of shale, split Hopkinson pressure bar (SHPB) and high-speed imaging and digital image correlation (DIC) technologies were adopted.
Qian Dong   +4 more
doaj   +1 more source

A Study of Mechanical Property of Artificial Frozen Clay under Dynamic Load

open access: yesAdvances in Civil Engineering, 2018
To determine the mechanical properties of artificial frozen clay under dynamic load, 81 triaxial shear tests were carried out for artificial frozen clay at different temperatures, amplitudes, frequencies, and precompressions and three kinds of testing ...
Dongwei Li, Juhong Fan
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Machine Learning Applications in the Mechanical Analysis of Nanomaterials and Nanostructures

open access: yesApplied Sciences
Machine learning (ML) is increasingly used to address the computational complexity and multiscale nature of mechanical analysis in nanomaterials and nanostructures. Traditional analytical, numerical, and atomistic approaches, such as continuum mechanics,
Mostafa Sadeghian   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Application of dynamic mechanical analysis for the study of viscoelastic properties and identification of softwood and hardwood species [PDF]

open access: yesEPJ Web of Conferences
Based on experimental studies using dynamic mechanical analysis (DMA) methods, the storage modulus E', loss modulus E", and mechanical loss coefficient tan δ were determined.
Tyurin Alexander   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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